Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 6/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL142211 | 1.00 | GRIN2B (0.43) | GRIN2BNAAAADAM17S1PR5 | |
| SCHEMBL145242 | 0.89 | GRIN2B (0.45) | GRIN2BNAAAADAM17S1PR5 | |
| SCHEMBL145119 | 0.87 | GRIN2B (0.43) | GRIN2BNAAAADAM17 | |
| SCHEMBL141076 | 0.85 | GRIN2B (0.42) | GRIN2BNAAAADAM17S1PR5 | |
| SCHEMBL144742 | 0.84 | GRIN2B (0.42) | GRIN2BNAAAADAM17 | |
| SCHEMBL143089 | 0.81 | GRIN2B (0.42) | GRIN2BNAAAADAM17 | |
| SCHEMBL3402984 | 0.81 | GRIN2B (0.42) | GRIN2BNAAAADAM17 | |
| SCHEMBL26695056 | 0.75 | NAAA (0.40) | GRIN2BNAAA | |
| SCHEMBL26695170 | 0.75 | NAAA (0.40) | GRIN2BNAAA | |
| SCHEMBL16402974 | 0.72 | GRIN2B (0.36) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250171-A2 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | Achaogen, Inc. (US) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009137130-A2 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2009-11-12 | — | — | WO | disclosed |