Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | CCNC | P24863 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314831 | 1.00 | PIK3C3 (0.33) | PIK3C3GRM5CYP1A2CYP19A1CYP3A4 | |
| SCHEMBL3393977 | 0.89 | PIK3C3 (0.31) | PIK3C3GRM5CYP3A4PRKACAROCK1 | |
| SCHEMBL314743 | 0.89 | PIK3C3 (0.31) | PIK3C3GRM5CYP3A4PRKACAROCK1 | |
| SCHEMBL314632 | 0.88 | MKNK1 (0.34) | CYP11B2CYP11B1 | |
| SCHEMBL314631 | 0.88 | MKNK1 (0.34) | CYP11B2CYP11B1 | |
| SCHEMBL3399023 | 0.88 | CYP11B2 (0.32) | CYP11B2CYP11B1GSK3BDYRK1A | |
| SCHEMBL316078 | 0.88 | CYP11B2 (0.32) | CYP11B2CYP11B1GSK3BDYRK1A | |
| SCHEMBL3400456 | 0.86 | MKNK1 (0.33) | CYP11B2 | |
| SCHEMBL315665 | 0.86 | MKNK1 (0.33) | CYP11B2 | |
| SCHEMBL314932 | 0.85 | AAK1 (0.33) | CYP3A4ROCK1CCNCCDK8GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |