Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314743 | 1.00 | PIK3C3 (0.31) | PIK3C3DYRK1AROCK2MAPTCYP3A4 | |
| SCHEMBL314831 | 0.89 | PIK3C3 (0.33) | PIK3C3DYRK1ACYP3A4PRKACAROCK1 | |
| SCHEMBL3400544 | 0.89 | PIK3C3 (0.33) | PIK3C3DYRK1ACYP3A4PRKACAROCK1 | |
| SCHEMBL2410974 | 0.89 | ROCK2 (0.36) | ROCK2CYP3A4PRKACAROCK1GRM5 | |
| SCHEMBL2410970 | 0.89 | ROCK2 (0.36) | ROCK2CYP3A4PRKACAROCK1GRM5 | |
| SCHEMBL314632 | 0.88 | MKNK1 (0.34) | CYP11B2CYP11B1 | |
| SCHEMBL314631 | 0.88 | MKNK1 (0.34) | CYP11B2CYP11B1 | |
| SCHEMBL3397066 | 0.88 | CYP11B2 (0.32) | DYRK1ACYP11B2CYP11B1GSK3B | |
| SCHEMBL314556 | 0.88 | CYP11B2 (0.32) | DYRK1ACYP11B2CYP11B1GSK3B | |
| SCHEMBL314511 | 0.87 | WNT3A (0.34) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |