Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15926056 | 0.84 | GAA (0.49) | TSHRNPSR1GAACYP2C9CYP2C19 | |
| SCHEMBL17476633 | 0.82 | HDAC4 (0.45) | CHRM1TSHRNPSR1GAACYP2C9 | |
| SCHEMBL22734518 | 0.82 | TSHR (0.46) | TSHRNPSR1GAACYP2C9CYP2C19 | |
| SCHEMBL4940386 | 0.82 | TSHR (0.46) | TSHRNPSR1GAACYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL22734575 | 0.81 | CHRM1 (0.45) | CHRM1TSHRPOLBALDH1A1KMT2A | |
| SCHEMBL22734625 | 0.75 | KMT2A (0.38) | CHRM1HDAC4HDAC6POLBALDH1A1 | |
| SCHEMBL1893522 | 0.74 | HDAC4 (0.45) | CHRM1HDAC4HDAC6POLBALDH1A1 | |
| Trimethylammonium SCHEMBL22734573 | 0.74 | KMT2A (0.37) | CHRM1POLBALDH1A1KMT2A | |
| SCHEMBL4941108 | 0.72 | CHRM1 (0.41) | CHRM1TSHRPOLBPKMALDH1A1 | |
| SCHEMBL2530974 | 0.70 | POLB (0.40) | CHRM1CYP2C9CYP2C19POLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200386767-A1 | Analytical method and apparatus using fingerprints on the basis of types in expression levels of express trace proteins and/or peptides contained in living tissue and/or biological fluid | SHINWA CHEMICAL INDUSTRIES LTD. (JP) | 2020-12-10 | — | — | US | disclosed |
| US-9108923-B2 | Compounds, compositions, and methods for cancer therapy | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2015-08-18 | — | — | US | disclosed |
| US-20140024639-A1 | Compounds, Compositions, and Methods for Cancer Therapy | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-01-23 | — | — | US | disclosed |
| JP-2010071986-A | FLUORESCENCE REAGENT | IMAI KAZUHIRO | 2010-04-02 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140024639-A1 | Compounds, Compositions, and Methods for Cancer Therapy | MCL1, TP53, VHL | CHRM1 4868/4885TSHR 4818/4885NPSR1 3122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.