Trimethylammonium

Trimethylammonium

SCHEMBL22734573

CC(Cl)NS(=O)(=O)c1ccc(F)c2nonc12.CN(C)C

nearest known ligand 0.37

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.37
POLB P06746 2/20 0.37
CHRM1 P11229 3/20 0.35
RORA P35398 1/20 0.35
RORC P51449 1/20 0.35
NR1H2 P55055 1/20 0.35
NLRP3 Q96P20 2/20 0.33
EPAS1 Q99814 2/20 0.33
ALDH1A1 P00352 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
CHRM2 P08172 2/20 0.32
RRM1 P23921 2/20 0.32
RRM2B Q7LG56 2/20 0.32
CCR2 P41597 1/20 0.32
GFER P55789 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22734625 0.85 KMT2A (0.38) KMT2APOLBCHRM1RORARORC
Trimethylammonium SCHEMBL22734514 0.85 RORA (0.46) KMT2APOLBRORARORCNR1H2
Trimethylammonium SCHEMBL22734668 0.82 NLRP3 (0.33) CHRM1NLRP3L3MBTL1CHRM2RRM1
Trimethylammonium SCHEMBL22734552 0.82 MAPT (0.37) KMT2APOLBNLRP3ALDH1A1
Hydrochloric Acid SCHEMBL22734577 0.79 KMT2A (0.37) KMT2APOLBCHRM1RORARORC
SCHEMBL1893522 0.74 HDAC4 (0.45) KMT2APOLBCHRM1EPAS1ALDH1A1
SCHEMBL3400848 0.74 CHRM1 (0.48) KMT2APOLBCHRM1ALDH1A1
SCHEMBL6430746 0.74 CHRM1 (0.41) KMT2APOLBCHRM1RORARORC
SCHEMBL4941108 0.72 CHRM1 (0.41) KMT2APOLBCHRM1RORARORC
SCHEMBL22734597 0.72 RORA (0.46) KMT2APOLBRORARORCNR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200386767-A1 Analytical method and apparatus using fingerprints on the basis of types in expression levels of express trace proteins and/or peptides contained in living tissue and/or biological fluid SHINWA CHEMICAL INDUSTRIES LTD. (JP) 2020-12-10 US disclosed