SCHEMBL1893522

SCHEMBL1893522

CN(C)S(=O)(=O)c1ccc(F)c2nonc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 4/20 0.45
HDAC6 Q9UBN7 4/20 0.45
HDAC3 O15379 3/20 0.45
HDAC1 Q13547 3/20 0.45
HDAC7 Q8WUI4 3/20 0.45
HDAC2 Q92769 3/20 0.45
HDAC10 Q969S8 3/20 0.45
HDAC11 Q96DB2 3/20 0.45
HDAC8 Q9BY41 3/20 0.45
HDAC9 Q9UKV0 3/20 0.45
HDAC5 Q9UQL6 3/20 0.45
EPAS1 Q99814 1/20 0.40
POLB P06746 2/20 0.40
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 2/20 0.33
ALOX5AP P20292 2/20 0.33
FEN1 P39748 2/20 0.33
HTT P42858 1/20 0.33
CHRM1 P11229 1/20 0.33
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3501251 0.80 HDAC3 (0.45) HDAC4HDAC6HDAC3HDAC1HDAC7
SCHEMBL2530974 0.79 POLB (0.40) EPAS1POLBKMT2AALDH1A1CHRM1
SCHEMBL23598356 0.78 HDAC1 (0.55) HDAC4HDAC6HDAC3HDAC1HDAC7
SCHEMBL10693669 0.77 POLB (0.37) EPAS1POLBKMT2AALDH1A1CHRM1
SCHEMBL571688 0.77 TET2 (0.46) POLBKMT2AALDH1A1HTTCHRM1
SCHEMBL9780063 0.76 HDAC1 (0.54) HDAC4HDAC6HDAC3HDAC1HDAC7
Ammonia Solution, Strong SCHEMBL591415 0.76 TET2 (0.45) HDAC4HDAC6HDAC3HDAC1HDAC7
SCHEMBL22734625 0.75 KMT2A (0.38) HDAC4HDAC6HDAC3HDAC1HDAC7
SCHEMBL3400848 0.74 CHRM1 (0.48) HDAC4HDAC6POLBKMT2AALDH1A1
Trimethylammonium SCHEMBL22734573 0.74 KMT2A (0.37) EPAS1POLBKMT2AALDH1A1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116375661-B Water-soluble environment-sensitive fluorescent probe and preparation method and application thereof 江苏师范大学 2025-03-11 CN claimed
CN-116375661-A Water-soluble environment-sensitive fluorescent probe and preparation method and application thereof 江苏师范大学 2023-07-04 CN claimed
WO-2001047485-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-07-05 WO claimed
JP-6184141-A None JP disclosed
US-12638394-B2 Skin sensitization measuring reagent, method for measuring skin sensitization, and compound FUJIFILM CORPORATION (JP) 2026-05-26 US disclosed
EP-4443155-B1 ENCAPSULATED PRE-ANALYTIC WORKFLOWS FOR FLOW-THROUGH DEVICES, LIQUID CHROMATOGRAPHY AND MASS SPECTROMETRIC ANALYSIS WATERS TECHNOLOGIES CORP (US) 2026-05-13 EP disclosed
US-12487210-B2 Encapsulated pre-analytic workflows for flow-through devices, liquid chromatography and mass spectrometric analysis WATERS TECHNOLOGIES CORPORATION (US) 2025-12-02 US disclosed
US-20250188033-A1 INHIBITOR OF REPLICATION PROTEIN A1 OF TRYPANOSOMA BRUCEI AND METHOD OF USE THEREOF UNIVERSIDAD NACIONAL DE SAN MARTIN (AR) 2025-06-12 US disclosed
CN-116375661-B Water-soluble environment-sensitive fluorescent probe and preparation method and application thereof 江苏师范大学 2025-03-11 CN disclosed
EP-4036570-B1 REAGENT FOR MEASURING SKIN SENSITIZATION, METHOD FOR MEASURING SKIN SENSITIZATION, AND COMPOUND FUJIFILM CORP (JP) 2025-03-05 EP disclosed
CN-118792277-A DNA polymerase mutant, fusion protein and application thereof 华南理工大学 2024-10-18 CN disclosed
US-20110189708-A1 METHOD FOR EVALUATING SPECIFIC INCORPORATION OF D-GLUCOSE INTO CELLS HIROSAKI UNIVERSITY (JP) 2011-08-04 US disclosed
EP-2325327-A1 METHOD FOR EVALUATING SPECIFIC INCORPORATION OF D-GLUCOSE INTO CELLS Hirosaki University (JP) 2011-05-25 EP disclosed
US-20100099134-A1 METHODS FOR DETECTING SULFHYDRYL-CONTAINING COMPOUNDS IN A BIOLOGICAL TEST SAMPLE THERAVANCE BIOPHARMA R&D IP, LLC 2010-04-22 US disclosed
EP-1948819-B1 DIAMINE OXIDASE DETERMINATION SCIOTEC DIAGNOSTIC TECHNOLOGIE (AT) 2009-04-15 EP disclosed
US-20080306126-A1 Peroxisome proliferator activated receptor treatment of hyperhomocysteinemia and its complications FONSECA VIVIAN A 2008-12-11 US disclosed
US-20080227116-A1 Histaminase Determination Missbichler, Albert (AT) 2008-09-18 US disclosed
EP-1948819-A1 HISTAMINASE DETERMINATION Missbichler, Albert (AT) 2008-07-30 EP disclosed
WO-2007056788-A1 HISTAMINASE DETERMINATION MISSBICHLER ALBERT (AT) 2007-05-24 WO disclosed
JP-H06184141-A NEW OPTICALLY ACTIVE@(3754/24)+)-AND (-)-4-(N,N-DIMETHYLAMINOSULFONYL)-7-(2-CHLOROFORMYLPYRROLIDIN-1-YL)-2,1,3-BENZOXADIAZOLE TOKYO KASEI KOGYO KK 1994-07-05 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110189708-A1 METHOD FOR EVALUATING SPECIFIC INCORPORATION OF D-GLUCOSE INTO CELLS SLC2A4, SLC2A3, SLC2A1 HDAC4 3382/4885HDAC6 3662/4885HDAC3 2797/4885
US-12638394-B2 Skin sensitization measuring reagent, method for measuring skin sensitization, and compound HRH1, HRH4, CUTA HDAC4 4602/4885HDAC6 4821/4885HDAC3 4825/4885
US-20250188033-A1 INHIBITOR OF REPLICATION PROTEIN A1 OF TRYPANOSOMA BRUCEI AND METHOD OF USE THEREOF RPA1, RPA3, POLR1A HDAC4 2833/4885HDAC6 2687/4885HDAC3 2152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.