Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28045296 | 0.63 | — | — | |
| SCHEMBL3877977 | 0.61 | NPC1 (0.30) | ALDH1A1 | |
| Bicarbonate SCHEMBL27675829 | 0.60 | — | — | |
| SCHEMBL3911165 | 0.60 | PTPN22 (0.34) | ALDH1A1 | |
| SCHEMBL3132605 | 0.59 | — | — | |
| SCHEMBL8082743 | 0.58 | — | — | |
| SCHEMBL560767 | 0.58 | — | — | |
| SCHEMBL11176641 | 0.55 | ACMSD (0.35) | — | |
| SCHEMBL6290262 | 0.55 | CFTR (0.35) | ALDH1A1 | |
| SCHEMBL502595 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010062506-A2 | DECAHYDRO-1H-INDENOQUINOLINONE AND DECAHYDRO-3H-CYCLOPENTAPHENANTHRIDINONE CYP17 INHIBITORS | LEAD THERAPEUTICS, INC. (US) | 2010-06-03 | — | — | WO | disclosed |