Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23089825 | 0.69 | ALDH1A1 (0.42) | ACMSDHDAC3HDAC1HDAC2 | |
| Bicarbonate SCHEMBL10441915 | 0.60 | ACMSD (0.49) | ACMSDHDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL10803110 | 0.60 | — | — | |
| Bicarbonate SCHEMBL2907611 | 0.60 | ACMSD (0.49) | ACMSDHDAC3HDAC4HDAC1HDAC7 | |
| Bicarbonate SCHEMBL10962051 | 0.60 | ACMSD (0.49) | ACMSDHDAC3HDAC4HDAC1HDAC7 | |
| Acrylic Acid SCHEMBL3057787 | 0.60 | LMNA (0.43) | ACMSDGRM2HDAC3HDAC4HDAC1 | |
| SCHEMBL28336519 | 0.60 | ACMSD (0.45) | ACMSDGRM2HDAC3HDAC1HDAC2 | |
| SCHEMBL25427300 | 0.59 | POLB (0.34) | — | |
| Methacrylic Acid SCHEMBL1155692 | 0.59 | ACMSD (0.41) | ACMSDGRM2HDAC3HDAC4HDAC1 | |
| SCHEMBL15048839 | 0.59 | TYMP (0.40) | ACMSDGRM2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4385180-A | 10,10a-Dihydro-1H-thiozino[4,3-a,]-indole-1,4(3H)-diones | AMERICAN HOME PRODUCTS CORPORATION (US) | 1983-05-24 | — | — | US | disclosed |