Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | MTOR | P42345 | 3/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315127 | 1.00 | RXFP1 (0.33) | RXFP1PIK3CAMTORNAAAGABRA1 | |
| SCHEMBL5275422 | 0.90 | RXFP1 (0.44) | RXFP1PIK3CAMTORNAAAGABRA1 | |
| SCHEMBL2138931 | 0.90 | RXFP1 (0.44) | RXFP1PIK3CAMTORNAAAGABRA1 | |
| SCHEMBL314247 | 0.89 | DGAT1 (0.35) | RXFP1PIK3CAMTORNAAAGABRA1 | |
| SCHEMBL3399096 | 0.89 | DGAT1 (0.35) | RXFP1PIK3CAMTORNAAAGABRA1 | |
| SCHEMBL314637 | 0.89 | CHRNA7 (0.32) | RXFP1CHRNA7CYP4F2CYP4A11 | |
| SCHEMBL314638 | 0.89 | CHRNA7 (0.32) | RXFP1CHRNA7CYP4F2CYP4A11 | |
| SCHEMBL314941 | 0.87 | CHRNA7 (0.35) | RXFP1PIK3CAMTORNAAACHRNA7 | |
| SCHEMBL3399328 | 0.87 | CHRNA7 (0.35) | RXFP1PIK3CAMTORNAAACHRNA7 | |
| SCHEMBL315460 | 0.86 | CHRNA7 (0.32) | RXFP1CHRNA7CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |