Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314247 | 1.00 | DGAT1 (0.35) | DGAT1MKNK1MKNK2RXFP1ADORA2A | |
| SCHEMBL5275422 | 0.91 | RXFP1 (0.44) | RXFP1PIK3CAMTORNAAAGABRA1 | |
| SCHEMBL2138931 | 0.91 | RXFP1 (0.44) | RXFP1PIK3CAMTORNAAAGABRA1 | |
| SCHEMBL315127 | 0.89 | RXFP1 (0.33) | RXFP1PIK3CAMTORNAAAGABRA1 | |
| SCHEMBL3401231 | 0.89 | RXFP1 (0.33) | RXFP1PIK3CAMTORNAAAGABRA1 | |
| SCHEMBL3399328 | 0.88 | CHRNA7 (0.35) | DGAT1RXFP1PIK3CAMTORNAAA | |
| SCHEMBL314941 | 0.88 | CHRNA7 (0.35) | DGAT1RXFP1PIK3CAMTORNAAA | |
| SCHEMBL315460 | 0.87 | CHRNA7 (0.32) | RXFP1CYP2A6CHRNA7 | |
| SCHEMBL3398167 | 0.87 | NAAA (0.33) | DGAT1RXFP1NAAACHRNA7 | |
| SCHEMBL315023 | 0.87 | NAAA (0.33) | DGAT1RXFP1NAAACHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |