Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 13/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314332 | 1.00 | ABL1 (0.35) | ABL1CYP11B2CYP11B1SLC22A12KIT | |
| SCHEMBL3395304 | 0.92 | ABL1 (0.35) | ABL1SLC22A12 | |
| SCHEMBL314154 | 0.92 | ABL1 (0.35) | ABL1SLC22A12 | |
| SCHEMBL2409998 | 0.90 | PRMT5 (0.37) | ABL1CYP11B2CYP11B1KITPDGFRA | |
| SCHEMBL2409995 | 0.90 | PRMT5 (0.37) | ABL1CYP11B2CYP11B1KITPDGFRA | |
| SCHEMBL3398727 | 0.88 | ABL1 (0.34) | ABL1CYP11B2SLC22A12 | |
| SCHEMBL316221 | 0.88 | ABL1 (0.34) | ABL1CYP11B2SLC22A12 | |
| SCHEMBL314631 | 0.87 | MKNK1 (0.34) | CYP11B2CYP11B1 | |
| SCHEMBL314632 | 0.87 | MKNK1 (0.34) | CYP11B2CYP11B1 | |
| SCHEMBL315649 | 0.85 | CHRNB1 (0.37) | ABL1CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |