Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316221 | 1.00 | ABL1 (0.34) | ABL1CCNCCDK8SLC22A12USP30 | |
| SCHEMBL2412492 | 0.90 | FFAR1 (0.36) | ABL1CCNCCDK8CTSAFFAR1 | |
| SCHEMBL2412489 | 0.90 | FFAR1 (0.36) | ABL1CCNCCDK8CTSAFFAR1 | |
| SCHEMBL314154 | 0.90 | ABL1 (0.35) | ABL1CCNCCDK8SLC22A12FFAR1 | |
| SCHEMBL3395304 | 0.90 | ABL1 (0.35) | ABL1CCNCCDK8SLC22A12FFAR1 | |
| SCHEMBL2140964 | 0.88 | CHRNB1 (0.33) | CTSA | |
| SCHEMBL2139910 | 0.88 | CHRNB1 (0.33) | CTSA | |
| SCHEMBL3401266 | 0.88 | ABL1 (0.35) | ABL1SLC22A12CYP11B2 | |
| SCHEMBL314332 | 0.88 | ABL1 (0.35) | ABL1SLC22A12CYP11B2 | |
| SCHEMBL2138226 | 0.87 | CYP11B2 (0.39) | CTSACYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |