Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 6/20 | 0.49 |
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.47 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3404671 | 0.88 | CNR1 (0.48) | EPHX2CNR1HRH3HTR2CNPC1 | |
| SCHEMBL3405357 | 0.88 | CNR1 (0.54) | PPARACNR1HRH3TARBP2HTR2C | |
| SCHEMBL3401619 | 0.87 | CNR1 (0.53) | PPARACNR1HRH3TARBP2HTR2C | |
| SCHEMBL3403012 | 0.86 | ALDH1A1 (0.56) | EPHX2PPARAPPARDCNR1PPARG | |
| SCHEMBL3399685 | 0.85 | CNR1 (0.55) | CNR1HRH3HTR2CNPC1GAA | |
| SCHEMBL3405399 | 0.85 | CNR1 (0.57) | CNR1HRH3TARBP2HTR2CNPC1 | |
| SCHEMBL13071718 | 0.84 | CNR1 (0.50) | PPARACNR1HRH3TARBP2PPARG | |
| SCHEMBL3399775 | 0.84 | CNR1 (0.58) | CNR1HRH3TARBP2HTR2CNPC1 | |
| SCHEMBL3402146 | 0.84 | TARBP2 (0.53) | CNR1HRH3TARBP2HTR2CALDH1A1 | |
| SCHEMBL3398840 | 0.84 | CNR1 (0.54) | CNR1HRH3TARBP2HTR2CNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
| WO-2006089076-A9 | THIAZOLE AMIDES, IMIDAZOLE AMIDES AND RELATED ANALOGUES | NEUROGEN CORP (US) | 2007-04-26 | — | — | WO | disclosed |