SCHEMBL340146

SCHEMBL340146

C=C(C)C(=O)OCC[Si](C)(C)OCC

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.55
TSHR P16473 5/20 0.49
ALDH1A1 P00352 5/20 0.40
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL64874 0.90 TSHR (0.54) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL16537350 0.88 TSHR (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL16286673 0.87 TSHR (0.60) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL16537163 0.87 TSHR (0.60) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL19124129 0.87 TSHR (0.60) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL65280 0.86 THRB (0.55) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL7940214 0.84 TSHR (0.49) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL10657395 0.84 THRB (0.58) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL15603423 0.84 TSHR (0.49) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL260933 0.84 THRB (0.56) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8053528-B2 Binder compositions for fiber mats, and fiber mats and articles comprising them GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-11-08 US claimed
US-7638075-B2 Colored printing ink for contact lenses NOVARTIS AG (CH) 2009-12-29 US claimed
US-20090124151-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-05-14 US claimed
EP-1381331-B1 METHOD FOR MAKING A COLORED CONTACT LENS NOVARTIS AG (CH) 2009-03-11 EP claimed
US-6955832-B2 Colored printing ink for contact lenses NOVARTIS AG (CH) 2005-10-18 US claimed
US-20050221105-A1 Colored printing ink for contact lenses ALCON INC. (CH) 2005-10-06 US claimed
EP-1381331-A2 COLORED PRINTING INK FOR CONTACT LENSES Novartis AG (CH) 2004-01-21 EP claimed
US-20030054109-A1 Colored printing ink for contact lenses NOVARTIS AG (CH) 2003-03-20 US claimed
WO-2002074186-A2 COLORED PRINTING INK FOR CONTACT LENSES NOVARTIS AG (CH) 2002-09-26 WO claimed
US-20240018358-A1 POLYSILOXANE-BASED RESIN AND UTILIZATION THEREOF KANEKA CORPORATION (JP) 2024-01-18 US disclosed
WO-2023119928-A1 METHOD FOR PRODUCING DISPERSION LIQUID OR SOLUTION IN WHICH WATER CONTAINING POLYSILOXANE-BASED RESIN SERVES AS MEDIUM 株式会社カネカ 2023-06-29 WO disclosed
CN-111533854-B Silicon modified acrylic resin and application thereof 上海亿祺化工技术有限公司 2023-03-31 CN disclosed
CN-112592634-B Laser layer coating for improving information reproduction of alumite and preparation method thereof 广东镭宝光电科技有限公司 2021-11-30 CN disclosed
CN-109803826-B Laminate and method for producing same 信越化学工业株式会社 2021-05-11 CN disclosed
US-20030054109-A1 Colored printing ink for contact lenses NOVARTIS AG (CH) 2003-03-20 US disclosed
US-20020190407-A1 System and method for treating articles with fluids ALCON INC. (CH) 2002-12-19 US disclosed
EP-1262306-A1 System and method for treating articles like ophthalmic lenses, contact lenses or medical devices with fluids Novartis AG (CH) 2002-12-04 EP disclosed
WO-2002074186-A2 COLORED PRINTING INK FOR CONTACT LENSES NOVARTIS AG (CH) 2002-09-26 WO disclosed
EP-1216142-A1 THERMOFORMABLE OPHTHALMIC LENS Wesley Jessen Corporation (US) 2002-06-26 EP disclosed
WO-2001005578-A1 THERMOFORMABLE OPHTHALMIC LENS WESLEY-JESSEN CORPORATION (US) 2001-01-25 WO disclosed