SCHEMBL65280

SCHEMBL65280

C=C(C)C(=O)OCC[Si](C)(OCC)OCC

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.55
TSHR P16473 5/20 0.49
ALDH1A1 P00352 5/20 0.40
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27550252 0.90 THRB (0.49) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL63717 0.90 TSHR (0.54) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL486167 0.88 TSHR (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL28347564 0.88 TSHR (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL2246405 0.88 TSHR (0.51) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL16223414 0.87 TSHR (0.60) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL16223433 0.87 TSHR (0.60) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL16223450 0.87 TSHR (0.60) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL16223407 0.87 TSHR (0.60) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL16223299 0.87 TSHR (0.60) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3340252-A1 ELECTRODE ASSEMBLY Solvay SA (BE) 2018-06-27 EP claimed
EP-3340253-A1 UV-RESISTANT ELECTRODE ASSEMBLY Solvay SA (BE) 2018-06-27 EP claimed
US-9181458-B2 Method for manufacturing optical film-forming pressure-sensitive adhesive layer, optical film-forming pressure-sensitive adhesive layer, pressure-sensitive adhesive-type optical film, and image display device NITTO DENKO CORPORATION (JP) 2015-11-10 US claimed
CN-101193988-B Curable composition and article possessing protective layer obtained therefrom SABIC INNOVATIVE PLASTICS IP 2012-07-18 CN claimed
EP-1893702-B1 CURABLE COMPOSITION AND SUBSTRATES POSSESSING PROTECTIVE LAYER OBTAINED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2011-07-20 EP claimed
CN-101189309-B Curable composition and substrates possessing protective layer obtained therefrom SABIC INNOVATIVE PLASTICS IP 2011-01-19 CN claimed
US-7638075-B2 Colored printing ink for contact lenses NOVARTIS AG (CH) 2009-12-29 US claimed
US-7622514-B2 curable formualtion containing a functionalized colloidal silica obtained from the reaction of surface hydroxyl groups of colloidal silica with at least one functionalizing silane, an acryalate monomer, a epoxy resin or polyepoxide, acrylate with epoxy functionality, a curing agent ( photoinitiators) SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-11-24 US claimed
EP-1381331-B1 METHOD FOR MAKING A COLORED CONTACT LENS NOVARTIS AG (CH) 2009-03-11 EP claimed
CN-101193988-A Curable composition and article possessing protective layer obtained therefrom MOMENTIVE PERFORMANCE MAT INC (US) 2008-06-04 CN claimed
CN-101111891-A Optical information storage medium possessing a multilayer coating GEN ELECTRIC (US) 2008-01-23 CN claimed
WO-2006121624-A1 CURABLE COMPOSITION AND ARTICLE POSSESSING PROTECTIVE LAYER OBTAINED THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2006-11-16 WO claimed
WO-2006121644-A1 OPTICAL INFORMATION STORAGE MEDIUM POSSESSING A MULTILAYER COATING GENERAL ELECTRIC COMPANY (US) 2006-11-16 WO claimed
US-20060251906-A1 Curable composition and article possessing protective layer obtained therefrom SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2006-11-09 US claimed
US-20060251848-A1 Optical information storage medium possessing a multilayer coating MOMENTIVE PERFORMANCE MATERIALS INC. 2006-11-09 US claimed
US-6955832-B2 Colored printing ink for contact lenses NOVARTIS AG (CH) 2005-10-18 US claimed
US-20050221105-A1 Colored printing ink for contact lenses ALCON INC. (CH) 2005-10-06 US claimed
EP-1381331-A2 COLORED PRINTING INK FOR CONTACT LENSES Novartis AG (CH) 2004-01-21 EP claimed
US-20030054109-A1 Colored printing ink for contact lenses NOVARTIS AG (CH) 2003-03-20 US claimed
WO-2002074186-A2 COLORED PRINTING INK FOR CONTACT LENSES NOVARTIS AG (CH) 2002-09-26 WO claimed