Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399750 | 0.80 | IDO1 (0.35) | IDO1CYP11B2TRPV1MAPK1TSHR | |
| SCHEMBL2817705 | 0.78 | CYP11B2 (0.45) | IDO1CYP11B2MAPK1TSHRMAPT | |
| SCHEMBL9497355 | 0.68 | CYP11B2 (0.42) | IDO1CYP11B2MAPK1TSHRMAPT | |
| SCHEMBL2818227 | 0.64 | CYP11B2 (0.58) | IDO1CYP11B2MAPK1TSHRALDH1A1 | |
| SCHEMBL2821137 | 0.64 | CYP11B2 (0.39) | IDO1CYP11B2MAPK1TSHRMAPT | |
| SCHEMBL2818670 | 0.63 | CYP11B2 (0.45) | IDO1CYP11B2MAPK1TSHRALDH1A1 | |
| SCHEMBL9493469 | 0.62 | CYP11B2 (0.45) | IDO1CYP11B2MAPK1TSHRALDH1A1 | |
| SCHEMBL9496956 | 0.61 | CYP11B2 (0.47) | IDO1CYP11B2MAPK1TSHRMAPT | |
| SCHEMBL68341 | 0.61 | CYP11B2 (0.47) | IDO1CYP11B2MAPK1TSHRMAPT | |
| SCHEMBL9493756 | 0.61 | CYP11B2 (0.47) | IDO1CYP11B2MAPK1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2213668-A2 | Imidazoles as aldosterone synthase inhibitors | Novartis AG (CH) | 2010-08-04 | — | — | EP | disclosed |