Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13182824 | 0.90 | HSD11B1 (0.85) | HSD11B1 | |
| SCHEMBL1971515 | 0.86 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL12571009 | 0.86 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL14972863 | 0.84 | HSD11B1 (0.79) | HSD11B1 | |
| SCHEMBL2008865 | 0.83 | HSD11B1 (0.83) | HSD11B1 | |
| SCHEMBL12571587 | 0.83 | HSD11B1 (0.83) | HSD11B1 | |
| SCHEMBL3237306 | 0.83 | HSD11B1 (0.84) | HSD11B1 | |
| SCHEMBL2007008 | 0.81 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL2004950 | 0.80 | HSD11B1 (0.75) | HSD11B1 | |
| SCHEMBL2003532 | 0.77 | HSD11B1 (0.71) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2233480-A1 | Chemical compounds | AstraZeneca AB (SE) | 2010-09-29 | — | — | EP | disclosed |