Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | F12 | P00748 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL546281 | 0.82 | GLA (0.39) | CA12CA1CA2GLACA3 | |
| SCHEMBL613954 | 0.80 | — | — | |
| Phenol SCHEMBL3402090 | 0.74 | TDP1 (0.52) | CA12CA1CA2GLACA3 | |
| SCHEMBL4895125 | 0.74 | — | — | |
| Phenol SCHEMBL447771 | 0.71 | CA12 (0.69) | CA12CA1CA2GLACA3 | |
| Phenol SCHEMBL8354282 | 0.71 | CA12 (0.69) | CA12CA1CA2GLACA3 | |
| Phenol SCHEMBL6918316 | 0.70 | CA12 (0.52) | CA12CA1CA2GLACA3 | |
| Phenol SCHEMBL679062 | 0.69 | CA12 (0.65) | CA12CA1CA2GLACA3 | |
| Phenol SCHEMBL10782891 | 0.69 | CA12 (0.65) | CA12CA1CA2GLACA3 | |
| Phenol SCHEMBL1921716 | 0.69 | CA12 (0.65) | CA12CA1CA2GLACA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1717314-B1 | Receptor for modified low-density lipoprotein | NIPPON CHEMIPHAR CO (JP) | 2010-10-06 | — | — | EP | disclosed |
| EP-1717314-A1 | Receptor for modified low-density lipoprotein | NIPPON CHEMIPHAR CO., LTD. (JP) | 2006-11-02 | — | — | EP | disclosed |
| EP-0795605-B1 | DENATURED LOW-DENSITY LIPOPROTEIN RECEPTOR | NIPPON CHEMIPHAR CO (JP) | 2006-06-14 | — | — | EP | disclosed |
| US-6197937-B1 | ANTIBODY WHICH PREFERENTIALLY BINDS MAMMALIAN BINDING PROTEIN; FOR THE TREATMENT OF ATHEROSCLEROSIS | NIPPON CHEMIPHAR CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| US-5962260-A | Recombinant production of human and bovine receptors for modified low-density lipoprotein | NIPPON CHEMIPHAR CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0795605-A1 | DENATURED LOW-DENSITY LIPOPROTEIN RECEPTOR | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-09-17 | — | — | EP | disclosed |