Phenol

Phenol

SCHEMBL6918316

N=C(N)NCl.Oc1ccccc1

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
GLA P06280 1/20 0.52
CA3 P07451 1/20 0.52
CA4 P22748 1/20 0.52
CA9 Q16790 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
CA14 Q9ULX7 1/20 0.52
F2 P00734 1/20 0.42
F10 P00742 1/20 0.42
F12 P00748 1/20 0.42
F7 P08709 1/20 0.42
F3 P13726 1/20 0.42
PKM P14618 1/20 0.42
LMNA P02545 2/20 0.41
BLM P54132 1/20 0.41
KMT2A Q03164 3/20 0.39
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL447771 0.82 CA12 (0.69) CA12CA1CA2GLACA3
Phenol SCHEMBL8354282 0.82 CA12 (0.69) CA12CA1CA2GLACA3
Phenol SCHEMBL1921716 0.79 CA12 (0.65) CA12CA1CA2GLACA3
Phenol SCHEMBL27501631 0.79 CA12 (0.65) CA12CA1CA2GLACA3
Phenol SCHEMBL887189 0.78 CA12 (0.55) CA12CA1CA2GLACA3
Phenol SCHEMBL27478117 0.78 CA12 (0.55) CA12CA1CA2GLACA3
Phenol SCHEMBL6009739 0.76 CA12 (0.52) CA12CA1CA2GLACA3
Phenol SCHEMBL11126561 0.76
Phenol SCHEMBL2382734 0.76 CA12 (0.92) CA12CA1CA2GLACA3
Phenol SCHEMBL28497921 0.75 CA12 (0.58) CA12CA1CA2GLACA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040167074-A1 Therapeutic applications of mFLINT polypeptides BUMOL THOMAS FRANK (US) 2004-08-26 US disclosed
EP-1140138-A2 THERAPEUTIC APPLICATIONS OF FLINT POLYPEPTIDES ELI LILLY AND COMPANY (US) 2001-10-10 EP disclosed
WO-2000037094-A2 THERAPEUTIC APPLICATIONS OF FLINT POLYPEPTIDES ELI LILLY AND COMPANY (US) 2000-06-29 WO disclosed
EP-0995759-A1 Angiopoietin related gene sequence scarface 2 ELI LILLY AND COMPANY (US) 2000-04-26 EP disclosed
WO-2000005241-A1 ANGIOPOIETIN RELATED GENE SEQUENCE SCARFACE 2 ELI LILLY AND COMPANY (US) 2000-02-03 WO disclosed
WO-1999062956-A1 ANGIOPOIETIN RELATED GENE SEQUENCE SCARFACE 3 ELI LILLY AND COMPANY (US) 1999-12-09 WO disclosed
WO-1999062925-A1 ANGIOPOIETIN RELATED GENE SEQUENCE SCARFACE 1 ELI LILLY AND COMPANY (US) 1999-12-09 WO disclosed
EP-0962530-A2 Gene sequence encoding for the angiopoietin related protein scarface 1 ELI LILLY AND COMPANY (US) 1999-12-08 EP disclosed
EP-0962466-A1 Angiopoietin related gene sequence scarface 3 ELI LILLY AND COMPANY (US) 1999-12-08 EP disclosed
WO-1999050413-A2 THERAPEUTIC APPLICATIONS OF MATURE FLINT (mFLINT) POLYPEPTIDES OR OPG3, A MEMBER OF THE TNF RECEPTOR SUPERFAMILY ELI LILLY AND COMPANY (US) 1999-10-07 WO disclosed
EP-0921194-A2 TRAILLK-2: a member of the TNF ligand family ELI LILLY AND COMPANY (US) 1999-06-09 EP disclosed
WO-1999026463-A2 TNF LIGAND FAMILY GENE ELI LILLY AND COMPANY (US) 1999-06-03 WO disclosed
WO-1999026976-A1 TNF LIGAND FAMILY GENE ELI LILLY AND COMPANY (US) 1999-06-03 WO disclosed
EP-0919620-A2 TRAILLK-3: a member of the TNF ligand family ELI LILLY AND COMPANY (US) 1999-06-02 EP disclosed
WO-1999023110-A1 HPTLG GENE FROM HUMAN HYPOTHALAMUS ELI LILLY AND COMPANY (US) 1999-05-14 WO disclosed
US-5639616-A POLYPEPTIDES, TRANSCRIPTION FACTORS ARCH DEVELOPMENT CORPORATION (US) 1997-06-17 US disclosed
WO-1995013373-A1 UBIQUITOUS NUCLEAR RECEPTOR: COMPOSITIONS AND METHODS ARCH DEVELOPMENT CORPORATION (US) 1995-05-18 WO disclosed