SCHEMBL340231

SCHEMBL340231

CC=CC(=O)OCCCCO[SiH](C)C

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.47
HCAR2 Q8TDS4 4/20 0.44
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 2/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HPGD P15428 1/20 0.36
APP P05067 4/20 0.34
PRKCA P17252 2/20 0.33
GSTP1 P09211 1/20 0.33
HTT P42858 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL340724 0.98 HCAR2 (0.46) ATMHCAR2TSHRALDH1A1CYP3A4
SCHEMBL20875236 0.86 ATM (0.60) ATMHCAR2TSHRALDH1A1CYP3A4
SCHEMBL8669692 0.86 ATM (0.60) ATMHCAR2TSHRALDH1A1CYP3A4
SCHEMBL15901752 0.85 ATM (0.47) ATMHCAR2TSHRALDH1A1CYP3A4
SCHEMBL25174772 0.84 ATM (0.64) ATMHCAR2TSHRALDH1A1CYP3A4
SCHEMBL20875241 0.84 ATM (0.58) ATMHCAR2TSHRALDH1A1CYP3A4
SCHEMBL28872434 0.84 ATM (0.58) ATMHCAR2TSHRALDH1A1CYP3A4
SCHEMBL340796 0.82 ATM (0.48) ATMHCAR2TSHRALDH1A1CYP3A4
SCHEMBL20913247 0.82 ATM (0.60) ATMHCAR2TSHRALDH1A1CYP3A4
SCHEMBL340573 0.81 HCAR2 (0.47) ATMHCAR2TSHRALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117209673-B Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2024-04-26 CN claimed
CN-117209673-A Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2023-12-12 CN claimed
US-6281297-B1 CONTAINING ALLYL METHACRYLATE AND ORGANOSILICON COMPOUND KANEKA CORPORATION (JP) 2001-08-28 US claimed
US-5616753-A Stabilizers for unsaturated, polymerizable organosilicon compounds OSI SPECIALTIES, INC. (US) 1997-04-01 US claimed
US-12030973-B2 Thermoplastic resin composition and molded article of same TECHNO-UMG CO., LTD. (JP) 2024-07-09 US disclosed
EP-3543246-B1 COMPOSITION CONTAINING ORGANIC SILICON COMPOUND AND PAINT AND ADHESIVE CONTAINING SAID COMPOSITION SHINETSU CHEMICAL CO (JP) 2024-05-15 EP disclosed
US-11976189-B2 Thermoplastic resin composition and molded article TECHNO-UMG CO., LTD. (JP) 2024-05-07 US disclosed
CN-117209673-B Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2024-04-26 CN disclosed
US-20240092961-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE OF SAME TECHNO-UMG CO., LTD. (JP) 2024-03-21 US disclosed
US-20240043678-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE TECHNO-UMG CO., LTD. (JP) 2024-02-08 US disclosed
EP-4317325-A1 RESIN COMPOSITION AND MOLDED BODY Mitsubishi Chemical Corporation (JP) 2024-02-07 EP disclosed
EP-4317309-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Techno-UMG Co., Ltd. (JP) 2024-02-07 EP disclosed
US-4994523-A Crosslinked graft polymer of polysiloxane and unsaturated compounds MITSUBISHI RAYON COMPANY LIMITED (JP) 1991-02-19 US disclosed
EP-0381239-A2 Impact-resistant resin MITSUBISHI RAYON COMPANY, LTD. (JP) 1990-08-08 EP disclosed
US-4918132-A Thermoplastic polyester resin composition MITSUBISHI RAYON COMPANY LIMITED (JP) 1990-04-17 US disclosed
US-4894415-A BLENDS, FRAFT COPOLYMERS, POLYALKYL (METH)ACRYLATE MITSUBISHI RAYON CO., LTD. (JP) 1990-01-16 US disclosed
US-4892900-A CONTAINING POLYSILOXANE GRAFT POLYMER, IMPROVED IMPACT STRENGTH MITSUBISHI RAYON CO., LTD. (JP) 1990-01-09 US disclosed
US-4888388-A BLENDS WITH POLYESTERS AND GRAFTED POLYSILOXANE-ACRYLIC POLYMERS MITSUBISHI RAYON COMPANY LIMITED (JP) 1989-12-19 US disclosed
EP-0308871-A2 Thermoplastic polyester resin composition MITSUBISHI RAYON CO., LTD. (JP) 1989-03-29 EP disclosed
US-4775712-A BLENDS WITH POLYSILOXANES-IMPACT STRENGTH, HEAT AND COLD RESISTANT, WEATHERPROOFING-MOLDING MATERIALS MITSUBISHI RAYON CO., LTD. (JP) 1988-10-04 US disclosed