Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 5/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669692 | 0.86 | ATM (0.60) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL20875236 | 0.86 | ATM (0.60) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL340231 | 0.85 | ATM (0.47) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL25174772 | 0.84 | ATM (0.64) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL20875241 | 0.84 | ATM (0.58) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL28872434 | 0.84 | ATM (0.58) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL340724 | 0.84 | HCAR2 (0.46) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL340796 | 0.82 | ATM (0.48) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL20913247 | 0.82 | ATM (0.60) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL10840160 | 0.81 | HCAR2 (0.44) | ATMHCAR2TSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170267703-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-09-21 | — | — | US | disclosed |
| US-9751901-B2 | Method for preparing a polyorganosiloxane and a polyorganosiloxane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-09-05 | — | — | US | disclosed |
| US-20170088566-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-03-30 | — | — | US | disclosed |
| US-20160159827-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SHINETSU CHEMICAL CO (JP) | 2016-06-09 | — | — | US | disclosed |
| US-9340649-B2 | Method for preparing a polyorganosiloxane and a polyorganosiloxane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-05-17 | — | — | US | disclosed |
| US-20150299397-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SHINETSU CHEMICAL CO (JP) | 2015-10-22 | — | — | US | disclosed |
| US-20140213809-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159827-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SCO2, HAO2, RIOX2 | ATM 2354/4885HCAR2 2218/4885TSHR 1922/4885 |
| US-20170088566-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SCO2, HAO2, RPS4X | ATM 2176/4885HCAR2 2239/4885TSHR 1832/4885 |
| US-20170267703-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SCO2, HAO2, RIOX2 | ATM 2354/4885HCAR2 2218/4885TSHR 1922/4885 |
| US-20140213809-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SCO2, IPO4, HAO2 | ATM 1327/4885HCAR2 3868/4885TSHR 3714/4885 |
| US-20150299397-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SCO2, HAO2, RIOX2 | ATM 2354/4885HCAR2 2218/4885TSHR 1922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.