SCHEMBL340239

SCHEMBL340239

NCCNCCC[SiH]1CCCCO1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.38
CA6 P23280 5/20 0.38
CA7 P43166 5/20 0.38
CA9 Q16790 5/20 0.38
CA14 Q9ULX7 5/20 0.38
CA5B Q9Y2D0 5/20 0.38
CA2 P00918 4/20 0.38
CA4 P22748 4/20 0.38
CA5A P35218 4/20 0.38
CA3 P07451 3/20 0.38
MEN1 O00255 2/20 0.36
RECQL P46063 2/20 0.36
KMT2A Q03164 2/20 0.36
LMNA P02545 3/20 0.34
ALOX15 P16050 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
CA1 P00915 2/20 0.34
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL21715561 0.98 CA12 (0.37) CA12CA6CA7CA9CA14
SCHEMBL687887 0.95 CA12 (0.40) CA12CA6CA7CA9CA14
SCHEMBL183518 0.83
SCHEMBL3823579 0.83 NFKB1 (0.30)
SCHEMBL9635674 0.81 CA12 (0.33) CA12CA6CA7CA9CA14
SCHEMBL15757857 0.78
SCHEMBL356969 0.76
SCHEMBL9388506 0.75
SCHEMBL8513105 0.75
SCHEMBL9635730 0.71 CA12 (0.35) CA12CA7CA9CA14CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112534011-B Aqueous, storage-stable compositions containing N-benzyl-substituted N- (2-aminoethyl) -3-aminopropylsiloxane hydrochloride, method for the production thereof and use thereof 赢创运营有限公司 2022-04-26 CN claimed
EP-3611236-B1 AN AQUEOUS, STORAGE-STABLE COMPOSITION CONTAINING N-BENZYL SUBSTITUTED N- (2-AMINOETHYL)-3-AMINOPROPYLSILOXANE-HYDROCHLORIDES, METHOD FOR THEIR PREPARATION AND THEIR USE EVONIK OPERATIONS GMBH (DE) 2020-09-30 EP claimed
EP-3611236-A1 AN AQUEOUS, STORAGE-STABLE COMPOSITION CONTAINING N-BENZYL SUBSTITUTED N- (2-AMINOETHYL)-3-AMINOPROPYLSILOXANE-HYDROCHLORIDES, METHOD FOR THEIR PREPARATION AND THEIR USE Evonik Operations GmbH (DE) 2020-02-19 EP claimed
US-20180200177-A1 STRAIGHTENING AGENT CONTAINING A POLYMER COMBINATION OF POLYURETHANES AND AMODIMETHICONES HENKEL AG & CO. KGAA (DE) 2018-07-19 US claimed
EP-3177367-A1 STRAIGHTENING AGENT CONTAINING A POLYMER COMBINATION OF POLYURETHANES AND AMODIMETHICONES Henkel AG & Co. KGaA (DE) 2017-06-14 EP claimed
WO-2016020108-A1 STRAIGHTENING AGENT CONTAINING A POLYMER COMBINATION OF POLYURETHANES AND AMODIMETHICONES HENKEL AG & CO. KGAA (DE) 2016-02-11 WO claimed
CN-109791375-B Reverse pattern forming composition, reverse pattern forming method, and device forming method 默克专利有限公司 2022-08-30 CN disclosed
CN-112534011-B Aqueous, storage-stable compositions containing N-benzyl-substituted N- (2-aminoethyl) -3-aminopropylsiloxane hydrochloride, method for the production thereof and use thereof 赢创运营有限公司 2022-04-26 CN disclosed
CN-112534011-A Aqueous, storage-stable compositions containing N-benzyl-substituted N- (2-aminoethyl) -3-aminopropylsiloxane hydrochloride, method for the production thereof and use thereof 赢创运营有限公司 2021-03-19 CN disclosed
EP-3611236-B1 AN AQUEOUS, STORAGE-STABLE COMPOSITION CONTAINING N-BENZYL SUBSTITUTED N- (2-AMINOETHYL)-3-AMINOPROPYLSILOXANE-HYDROCHLORIDES, METHOD FOR THEIR PREPARATION AND THEIR USE EVONIK OPERATIONS GMBH (DE) 2020-09-30 EP disclosed
US-10670969-B2 Reverse pattern formation composition, reverse pattern formation method, and device formation method AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2020-06-02 US disclosed
WO-2020035432-A1 AN AQUEOUS, STORAGE-STABLE COMPOSITION CONTAINING N-BENZYL-SUBSTITUTED N-(2-AMINOETHYL)-3-AMINOPROPYLSILOXANE HYDROCHLORIDES, PROCESSES FOR PRODUCTION THEREOF AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2020-02-20 WO disclosed
EP-3611236-A1 AN AQUEOUS, STORAGE-STABLE COMPOSITION CONTAINING N-BENZYL SUBSTITUTED N- (2-AMINOETHYL)-3-AMINOPROPYLSILOXANE-HYDROCHLORIDES, METHOD FOR THEIR PREPARATION AND THEIR USE Evonik Operations GmbH (DE) 2020-02-19 EP disclosed
US-8097602-B1 Method of treating body insect infestation HOST PHARMACEUTICALS, LLC (US) 2012-01-17 US disclosed
CN-101765687-A Granular materials for textile treatment DOW CORNING 2010-06-30 CN disclosed
US-20040115379-A1 Method of treating an elastomeric article KIMBERLY-CLARK WORLDWIDE, INC. 2004-06-17 US disclosed
US-4968760-A SILICON-CARBON BONDED RADICALS WITH BASIC NITROGEN WACKER-CHEMIE GMBH (DE) 1990-11-06 US disclosed
EP-0180464-B1 CONDITIONING SHAMPOO CONTAINING AMINE FUNCTIONAL POLYDIORGANOSILOXANE DOW CORNING CORPORATION (US) 1990-01-24 EP disclosed
EP-0180464-A2 Conditioning shampoo containing amine functional polydiorganosiloxane DOW CORNING CORPORATION (US) 1986-05-07 EP disclosed
US-4559227-A Conditioning shampoo containing amine functional polydiorganosiloxane DOW CORNING CORPORATION (US) 1985-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180200177-A1 STRAIGHTENING AGENT CONTAINING A POLYMER COMBINATION OF POLYURETHANES AND AMODIMETHICONES KRT18, PCNA, SMCHD1 CA12 2478/4885CA6 3907/4885CA7 2509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.