SCHEMBL9635674

SCHEMBL9635674

NCCCCC[SiH]1CCCCO1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA3 P07451 2/20 0.33
CA4 P22748 2/20 0.33
CA6 P23280 2/20 0.33
CA5A P35218 2/20 0.33
CA7 P43166 2/20 0.33
CA9 Q16790 2/20 0.33
CA14 Q9ULX7 2/20 0.33
CA5B Q9Y2D0 2/20 0.33
DNM1 Q05193 2/20 0.33
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3823579 0.98 NFKB1 (0.30)
SCHEMBL183518 0.94
SCHEMBL356969 0.91
SCHEMBL15757857 0.89
SCHEMBL687887 0.83 CA12 (0.40) CA12CA1CA2CA3CA4
SCHEMBL6679758 0.82 DNM1 (0.34) DNM1TSHR
SCHEMBL1464489 0.82 DNM1 (0.34) DNM1TSHR
SCHEMBL2902986 0.82 DNM1 (0.34) DNM1TSHR
SCHEMBL5335206 0.82 DNM1 (0.34) DNM1TSHR
SCHEMBL8928273 0.82 DNM1 (0.34) DNM1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0275707-B1 HAIR CARE COMPOSITION CONTAINING MODIFIED AMINOALKYL SUBSTITUTED POLYDIORGANOSILOXANE DOW CORNING CORPORATION (US) 1992-05-27 EP disclosed
EP-0275707-A2 Hair care composition containing modified aminoalkyl substituted polydiorganosiloxane DOW CORNING CORPORATION (US) 1988-07-27 EP disclosed
US-4749732-A Hair care composition containing modified aminoalkyl substituted polydiorganosiloxane DOW CORNING CORPORATION (US) 1988-06-07 US disclosed
EP-0095676-A2 Carboxylic acid-functional polysiloxane polymers, process for preparing the same and use thereof SWS Silicones Corporation (US) 1983-12-07 EP disclosed
EP-0095156-A2 Process for preparing quaternary ammonium-functional silicon compounds, products prepared thereof and use of the same Stauffer-Wacker Silicones Corporation (US) 1983-11-30 EP disclosed
US-4390713-A CATIONIC POLYMERS FROM A CARBOXYLIC ACID-CONTAINING POLYSILOXANE AND A HYDROXYL-CONTAINING AMMONIUM SALT; TEXTILE ANTISTATIC AGENTS SWS SILICONES CORPORATION (US) 1983-06-28 US disclosed