Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 7/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3402879 | 1.00 | MDM2 (0.48) | MDM2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL153106 | 0.85 | MDM2 (0.54) | MDM2TYRMAPTAPPCYBB | |
| SCHEMBL153105 | 0.85 | MDM2 (0.54) | MDM2TYRMAPTAPPCYBB | |
| SCHEMBL3409511 | 0.84 | MAPT (0.42) | MDM2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3409509 | 0.84 | MAPT (0.42) | MDM2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14889480 | 0.79 | CYBB (0.41) | MDM2CES1MAPTCYBBNOX4 | |
| SCHEMBL3405296 | 0.79 | CYBB (0.41) | MDM2CES1MAPTCYBBNOX4 | |
| SCHEMBL154460 | 0.77 | MDM2 (0.39) | MDM2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL154461 | 0.77 | MDM2 (0.39) | MDM2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL154459 | 0.77 | MDM2 (0.39) | MDM2PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |