Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYBB | P04839 | 1/20 | 0.41 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | TGM2 | P21980 | 4/20 | 0.40 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14889480 | 1.00 | CYBB (0.41) | CYBBNOX4CES1MDM2TGM2 | |
| SCHEMBL154459 | 0.83 | MDM2 (0.39) | CYBBNOX4MDM2BACE1MAPT | |
| SCHEMBL154460 | 0.83 | MDM2 (0.39) | CYBBNOX4MDM2BACE1MAPT | |
| SCHEMBL154461 | 0.83 | MDM2 (0.39) | CYBBNOX4MDM2BACE1MAPT | |
| SCHEMBL153105 | 0.81 | MDM2 (0.54) | CYBBNOX4MDM2MAPTMAPK1 | |
| SCHEMBL153106 | 0.81 | MDM2 (0.54) | CYBBNOX4MDM2MAPTMAPK1 | |
| SCHEMBL3402877 | 0.79 | MDM2 (0.48) | CYBBNOX4CES1MDM2MAPT | |
| SCHEMBL3402879 | 0.79 | MDM2 (0.48) | CYBBNOX4CES1MDM2MAPT | |
| SCHEMBL3409509 | 0.78 | MAPT (0.42) | CYBBNOX4MDM2BACE1MAPT | |
| SCHEMBL3409511 | 0.78 | MAPT (0.42) | CYBBNOX4MDM2BACE1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |