Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 2/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CYBB | P04839 | 1/20 | 0.47 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 3/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL153106 | 1.00 | MDM2 (0.54) | MDM2TYRMAPTALDH1A1ALOX15 | |
| SCHEMBL10848654 | 0.86 | TYR (0.57) | MDM2TYRMAPTALDH1A1ALOX15 | |
| SCHEMBL3402526 | 0.85 | MDM2 (0.48) | MDM2TYRMAPTALDH1A1ALOX15 | |
| SCHEMBL3403001 | 0.85 | MDM2 (0.48) | MDM2TYRMAPTALDH1A1HPGD | |
| SCHEMBL3402528 | 0.85 | MDM2 (0.48) | MDM2TYRMAPTALDH1A1ALOX15 | |
| SCHEMBL3402996 | 0.85 | MDM2 (0.48) | MDM2TYRMAPTALDH1A1HPGD | |
| SCHEMBL3402879 | 0.85 | MDM2 (0.48) | MDM2TYRMAPTALDH1A1HSD17B10 | |
| SCHEMBL3402877 | 0.85 | MDM2 (0.48) | MDM2TYRMAPTALDH1A1HSD17B10 | |
| SCHEMBL10849192 | 0.84 | TYR (0.56) | MDM2TYRMAPTALDH1A1ALOX15 | |
| SCHEMBL14889480 | 0.81 | CYBB (0.41) | MDM2MAPTMAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |