Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1062730 | 0.89 | KMT2A (0.46) | LMNAGAAMAPTMEN1KMT2A | |
| SCHEMBL3401272 | 0.86 | LMNA (0.51) | LMNAGPR35GAAMAPTTHRB | |
| SCHEMBL1063259 | 0.85 | MEN1 (0.43) | LMNAGAAMAPTMEN1KMT2A | |
| SCHEMBL1064330 | 0.79 | KMT2A (0.45) | LMNAGAAMAPTMEN1KMT2A | |
| SCHEMBL1062879 | 0.78 | KMT2A (0.47) | LMNAGAAMAPTMEN1KMT2A | |
| SCHEMBL3426735 | 0.76 | SMO (0.49) | LMNAGPR35MEN1KMT2AALDH1A1 | |
| SCHEMBL10314589 | 0.75 | KMT2A (0.41) | LMNAGAAMAPTMEN1KMT2A | |
| SCHEMBL10004581 | 0.73 | SMO (0.49) | LMNAGPR35MEN1KMT2AALDH1A1 | |
| SCHEMBL1061528 | 0.73 | LMNA (0.47) | LMNAGAAMAPTMEN1KMT2A | |
| SCHEMBL1057594 | 0.72 | LMNA (0.48) | LMNAGAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247588-A2 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009107850-A2 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-03 | — | — | WO | disclosed |