SCHEMBL3403577

SCHEMBL3403577

Oc1cccnc1C1=NCCN1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 13/20 0.51
CYP1A2 P05177 2/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1836133 0.77 KDM4E (0.61) NISCHKDM4E
SCHEMBL10473113 0.76 NISCH (0.45) NISCHKDM4E
SCHEMBL1882130 0.74 NISCH (0.62) NISCH
SCHEMBL9374955 0.73 NISCH (0.43) NISCHCYP1A2KDM4E
SCHEMBL29769309 0.73 KDM4E (0.55) KDM4E
SCHEMBL687180 0.73 KDM4E (0.55) KDM4E
SCHEMBL9375560 0.72 NISCH (0.61) NISCHCYP1A2KDM4E
SCHEMBL3399485 0.71 NISCH (0.51) NISCHKDM4E
SCHEMBL31234064 0.69 NISCH (0.61) NISCHCYP1A2KDM4E
SCHEMBL2385163 0.69 NISCH (0.61) NISCHCYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010018458-A2 PHENOL DERIVATIVES AND METHODS OF USE THEREOF CRYSTALGENOMICS, INC. (KR) 2010-02-18 WO claimed
WO-2010018458-A2 PHENOL DERIVATIVES AND METHODS OF USE THEREOF CRYSTALGENOMICS, INC. (KR) 2010-02-18 WO disclosed