Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.49 |
| ▸ | NISCH | Q9Y2I1 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | AGER | Q15109 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10473113 | 0.86 | NISCH (0.45) | KDM4ETDP1NISCHALDH1A1MAPT | |
| SCHEMBL9374955 | 0.84 | NISCH (0.43) | KDM4ETDP1NISCHACHE | |
| SCHEMBL1526540 | 0.78 | NISCH (0.60) | NISCH | |
| SCHEMBL270419 | 0.77 | KDM4E (1.00) | KDM4ETDP1NAPRTALDH1A1CYP3A4 | |
| SCHEMBL3403577 | 0.77 | NISCH (0.51) | KDM4ENISCH | |
| SCHEMBL8936695 | 0.76 | NISCH (0.41) | NISCHLMNA | |
| SCHEMBL30639818 | 0.75 | KDM4E (0.95) | KDM4ETDP1NAPRTALDH1A1CYP3A4 | |
| SCHEMBL29723448 | 0.75 | KDM4E (0.95) | KDM4ETDP1NAPRTALDH1A1CYP3A4 | |
| SCHEMBL30639802 | 0.75 | KDM4E (0.95) | KDM4ETDP1NAPRTALDH1A1CYP3A4 | |
| SCHEMBL9195272 | 0.75 | NISCH (0.53) | KDM4ENISCHALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4685003-B2 | — | — | 2011-05-18 | — | — | JP | claimed |
| US-7795439-B2 | saponifying a solution of pyridine-2,3-dicarboxylic acid ester with NaOH to form the sodium pyridine-2,3-dicarboxylate, reacting the solution with an oxidizing agent (H2O2, NaClO or NaBrO) to remove impurities, acidifying the solution with H2SO4 to produce pyridine-2,3-dicarboxylic acid herbicide | BASF AKTIENGESELLSCHAFT (DE) | 2010-09-14 | — | — | US | claimed |
| EP-1644333-B1 | IN-SITU TREATMENT OF PYRIDINE-2,3-DICARBOXYLIC ACID ESTERS WITH AN OXIDIZING AGENT | BASF SE (DE) | 2009-09-23 | — | — | EP | claimed |
| JP-2009514775-A | — | — | 2009-04-09 | — | — | JP | claimed |
| US-20070185331-A1 | In-situ treatment of pyridine 2,3-dicarboxylic acid esters with an oxidizing agent | BASF AKTIENGESELLSCHAFT (DE) | 2007-08-09 | — | — | US | claimed |
| EP-1644333-A1 | IN-SITU TREATMENT OF PYRIDINE-2,3-DICARBOXYLIC ACID ESTERS WITH AN OXIDIZING AGENT | BASF AKTIENGESELLSCHAFT (DE) | 2006-04-12 | — | — | EP | claimed |
| WO-2005005391-A1 | IN-SITU TREATMENT OF PYRIDINE-2,3-DICARBOXYLIC ACID ESTERS WITH AN OXIDIZING AGENT | BASF AKTIENGESELLSCHAFT (DE) | 2005-01-20 | — | — | WO | claimed |
| EP-0434965-B1 | Alkyl esters of 5-heterocyclic-pyridine-2,3-dicarboxylic acids and 5-heterocyclic 2-(2-imidazolin-2-yl) pyridines and methods for preparation thereof | AMERICAN CYANAMID CO (US) | 1998-05-20 | — | — | EP | claimed |
| US-4997947-A | Forming 6-substituted pyridine-2,3-dicarboxylic esters followed by reacting with aminoalkanecarboxylic acid amide; herbicides, plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | claimed |
| US-4891428-A | PRE-AND POSTEMERGENCE | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-01-02 | — | — | US | claimed |
| EP-0296109-A2 | Derivatives of 2-(imidazolin-2-yl)nicotinic acid | CIBA-GEIGY AG (CH) | 1988-12-21 | — | — | EP | claimed |
| US-4776876-A | Imidazolinyl derivatives having herbicidal activity | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-10-11 | — | — | US | claimed |
| JP-1135769-A | — | — | None | — | — | JP | disclosed |
| JP-1135768-A | — | — | None | — | — | JP | disclosed |
| JP-1139566-A | — | — | None | — | — | JP | disclosed |
| JP-5097810-A | — | — | None | — | — | JP | disclosed |
| EP-0212200-A2 | Pyridine derivatives and herbicidal composition | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1987-03-04 | — | — | EP | disclosed |
| US-4608079-A | Imidazolidinones, and imidazolidinethiones, process and intermediates for the preparation thereof, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1986-08-26 | — | — | US | disclosed |
| EP-0133310-A1 | Imidazolidinones, and imidazolidinethiones, process for the preparation thereof, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1985-02-20 | — | — | EP | disclosed |
| US-4439607-A | FROM THE DIACID AND PHOSGENE; DIMETHYLFORMAMIDE CATALYST | AMERICAN CYANAMID COMPANY (US) | 1984-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185331-A1 | In-situ treatment of pyridine 2,3-dicarboxylic acid esters with an oxidizing agent | HAO2, NOX4, IDH2 | KDM4E 2908/4885TDP1 1570/4885NAPRT 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.