Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 17/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417021 | 0.78 | CCR1 (0.40) | — | |
| SCHEMBL4478005 | 0.77 | IRAK4 (0.34) | IRAK4 | |
| SCHEMBL413086 | 0.77 | ENPP3 (0.39) | — | |
| SCHEMBL5615371 | 0.77 | — | — | |
| SCHEMBL855838 | 0.77 | HPGD (0.36) | IRAK4 | |
| SCHEMBL904725 | 0.76 | HPGDS (0.43) | HPGDSIRAK4PTGER4 | |
| SCHEMBL29533363 | 0.75 | HTR2C (0.35) | — | |
| SCHEMBL12147023 | 0.75 | PARP1 (0.34) | — | |
| SCHEMBL5055520 | 0.73 | PTGER4 (0.38) | PTGER4 | |
| SCHEMBL30643452 | 0.73 | KCNH2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2251341-A1 | Heterocyclic Janus kinase 3 inhibitors | Astellas Pharma Inc. (JP) | 2010-11-17 | — | — | EP | disclosed |