SCHEMBL340398

SCHEMBL340398

COc1cc(C(N)=O)ccc1O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.72
KMT2A Q03164 2/20 0.72
SLC22A6 Q4U2R8 1/20 0.72
SLC22A8 Q8TCC7 1/20 0.72
RAB9A P51151 1/20 0.72
HTT P42858 1/20 0.70
MAPK1 P28482 2/20 0.60
HSD17B2 P37059 1/20 0.60
CYP1A2 P05177 2/20 0.58
HSP90AA1 P07900 1/20 0.58
HSP90AB1 P08238 1/20 0.58
BLM P54132 1/20 0.58
KDM4E B2RXH2 1/20 0.57
POLB P06746 1/20 0.57
HDAC6 Q9UBN7 1/20 0.57
ALDH1A1 P00352 2/20 0.55
HPGD P15428 2/20 0.55
HSD17B10 Q99714 2/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2C9 P11712 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29428890 1.00 MEN1 (0.72) MEN1KMT2ASLC22A6SLC22A8RAB9A
Hydrochloric Acid SCHEMBL8337978 0.98 MEN1 (0.70) MEN1KMT2ASLC22A6SLC22A8RAB9A
Vanillic Acid SCHEMBL28735586 0.93 HTT (0.83) MEN1KMT2ASLC22A6SLC22A8RAB9A
Formamide SCHEMBL8336930 0.93 SLC22A6 (0.64) MEN1KMT2ASLC22A6SLC22A8RAB9A
SCHEMBL29415167 0.86 MAPK1 (0.77) HTTMAPK1CYP1A2POLBALDH1A1
SCHEMBL335681 0.86 MAPK1 (0.77) HTTMAPK1CYP1A2POLBALDH1A1
SCHEMBL2905586 0.85 RECQL (0.64) MEN1KMT2ASLC22A6SLC22A8RAB9A
Hydrochloric Acid SCHEMBL5154533 0.84 MAPK1 (0.74) HTTMAPK1CYP1A2POLBALDH1A1
SCHEMBL15289000 0.84 MEN1 (1.00) MEN1KMT2ASLC22A6SLC22A8RAB9A
SCHEMBL15814046 0.84 SLC22A6 (1.00) MEN1KMT2ASLC22A6SLC22A8RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1310 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325533-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS LLC (US) 2025-10-23 US claimed
EP-2222289-B2 TREATMENT OF ORAL PHARYNGEAL DYSPHAGIA NESTLE SA (CH) 2025-05-14 EP claimed
CN-118724760-A Preparation method of amido guanidine compound and myocardial protection effect thereof 天津理工大学 2024-10-01 CN claimed
CN-118549544-A Separation method of chemical components in capsicum and preparation thereof or construction method of characteristic spectrum 华润三九现代中药制药有限公司 2024-08-27 CN claimed
US-11896587-B2 Tryptamine compositions for enhancing neurite outgrowth TURTLE BEAR HOLDINGS, LLP (US) 2024-02-13 US claimed
CN-116837016-B Method for constructing recombinant escherichia coli engineering strain for producing capsaicin-vanilla nonanamide, recombinant strain and application 中国农业科学院北京畜牧兽医研究所 2024-01-02 CN claimed
EP-3494104-B1 WARMING SENSATION COMPOUNDS TAKASAGO PERFUMERY CO LTD (JP) 2023-11-15 EP claimed
CN-117045609-A Preparation method of vitamin C tablet 广州播恩维生素有限公司 2023-11-14 CN claimed
CN-116837016-A Method for constructing recombinant escherichia coli engineering strain for producing capsaicin-vanilla nonanamide, recombinant strain and application 中国农业科学院北京畜牧兽医研究所 2023-10-03 CN claimed
EP-3335693-B1 COMPOSITION FOR EXTERNAL USE OTSUKA PHARMA CO LTD (JP) 2023-09-13 EP claimed
US-5273754-A A mixture of a heating carminative, vanillylamide, and a cooling carminative, e.g. mint MANN MORRIS A (US) 1993-12-28 US claimed
WO-1993023061-A1 THERAPEUTIC USES OF PUNGENT BOTANICALS AND THEIR RELATED COMPOUNDS STAGGS JEFF J (US) 1993-11-25 WO claimed
EP-0546078-A4 BIRDFOOD CONTAINING CAPSAICIN OR ITS DERIVATIVES OR ANALOGUES US HEALTH (US) 1993-09-15 EP claimed
US-5221692-A Antinociceptives NATIONAL SCIENCE COUNCIL (TW) 1993-06-22 US claimed
EP-0546078-A1 BIRDFOOD CONTAINING CAPSAICIN OR ITS DERIVATIVES OR ANALOGUES THE UNITED STATES OF AMERICA as represented by the Secretary UNITED STATES DEPARTMENT OF COMMERCE (US) 1993-06-16 EP claimed
WO-1992003923-A1 BIRDFOOD CONTAINING CAPSAICIN OR ITS DERIVATIVES OR ANALOGUES THE UNITED STATES OF AMERICA, represented by THE SCRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) 1992-03-19 WO claimed
EP-0242827-B1 SURFACE SHAPED THERAPEUTIC SYSTEM, METHOD FOR ITS MANUFACTURE, AND ITS APPLICATION Lohmann GmbH & Co. KG (DE) 1991-12-27 EP claimed
US-4789687-A FOR REDUCTION OR PREVENTION OF BODY FAT ACCUMULATION AJINOMOTO CO., INC. (JP) 1988-12-06 US claimed
US-4680313-A Acceleration of lipid metabolism using vanillylamine derivatives AJINOMOTO CO., INC. (JP) 1987-07-14 US claimed
EP-0045280-B1 COMPOSITION FOR THE CONTROL OF SLUGS AND SNAILS, CONTAINER FOR THIS COMPOSITION AND USE OF SUBSTANCES IN PESTICIDES FOR SLUGS AND SNAILS SIPURO AG (CH) 1985-04-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11896587-B2 Tryptamine compositions for enhancing neurite outgrowth HTR1B, HTR6, BDNF MEN1 1443/4885KMT2A 2403/4885SLC22A6 2984/4885
US-20250325533-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, BDNF, HTR6 MEN1 1889/4885KMT2A 1859/4885SLC22A6 3549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.