SCHEMBL3404151

SCHEMBL3404151

O=C(Cl)N1CCCC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11189347 0.93 LMNA (0.52)
SCHEMBL5281622 0.91 LMNA (0.50)
SCHEMBL10630403 0.91 LMNA (0.50)
SCHEMBL2594237 0.80 LMNA (0.64)
SCHEMBL27896476 0.79
SCHEMBL59155 0.78
SCHEMBL3149604 0.78
SCHEMBL2297517 0.76 LMNA (0.59)
SCHEMBL1700875 0.76 LMNA (0.59)
SCHEMBL2705725 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0156079-A2 Polyether polyoxyalkylene prepolymers and block copolymers made therefrom SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-10-02 EP claimed
JP-60112825-A None JP disclosed
CN-122094953-A 1, 3-Dihydro-2H-pyrrolo [3,4-c ] quinoline derivatives as cGAS inhibitors for the treatment of inflammatory and/or autoimmune diseases 2026-05-26 CN disclosed
WO-2025040569-A1 1,3-DIHYDRO-2H-PYRROLO[3,4-C]QUINOLINE DERIVATIVES AS CGAS INHIBITORS FOR THE TREATMENT OF INFLAMMATORY AND/OR AUTOIMMUNE DISEASES KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2025-02-27 WO disclosed
US-20240270762-A1 PENICILLIN-BINDING PROTEIN INHIBITORS SPRING MILL PHARMA, INC. 2024-08-15 US disclosed
EP-4347607-A1 PENICILLIN-BINDING PROTEIN INHIBITORS Venatorx Pharmaceuticals, Inc. (US) 2024-04-10 EP disclosed
CN-117693511-A Penicillin binding protein inhibitors 维纳拓尔斯制药公司 2024-03-12 CN disclosed
CN-104387358-B Barrenwort glycosides compounds and application thereof 广东东阳光药业有限公司 2016-08-24 CN disclosed
CN-104387358-A Icariin compounds and application thereof GUANGDONG HEC PHARMACEUTICAL 2015-03-04 CN disclosed
EP-2250167-A1 ARYLMETHYLIDENE HETEROCYCLES AS NOVEL ANALGESICS Chlorion Pharma, Inc. (CA) 2010-11-17 EP disclosed
EP-0147051-A2 Production of polyether-polyamide block copolymers and prepolymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-07-03 EP disclosed
JP-S60112825-A PREPARATION OF POLYETHER POLYAMIDE BLOCK COPOLYMER SUMITOMO CHEM CO LTD 1985-06-19 JP disclosed
US-4016282-A BACTERICIDES BAYER AKTIENGESELLSCHAFT (DT) 1977-04-05 US disclosed
US-3980792-A EFFECTIVE AGAINST GRAM-NEGATIVE AND GRAM-POSITIVE INFECTIONS BAYER AKTIENGESELLSCHAFT (DT) 1976-09-14 US disclosed
US-3978223-A UREIDOACETAMIDO-PENICILLINS FOR TREATING BACTERIAL INFECTIONS BAYER AKTIENGESELLSCHAFT (DT) 1976-08-31 US disclosed
US-3974140-A BACTERICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-08-10 US disclosed
US-3959258-A BACTERICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 US disclosed
US-3939149-A BACTERICIDE BAYER AKTIENGESELLSCHAFT (DT) 1976-02-17 US disclosed
US-3936442-A ANTIBIOTIC BAYER AKTIENGESELLSCHAFT (DT) 1976-02-03 US disclosed
US-3933795-A Ureidoacetamido-penicillins Konig, Hans-Bodo (DT) 1976-01-20 US disclosed