Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29255120 | 1.00 | KMT2A (0.50) | KMT2AMEN1ALDH1A1PTPN1MAPK1 | |
| Hydrochloric Acid SCHEMBL4228454 | 0.98 | KMT2A (0.49) | KMT2AMEN1ALDH1A1PTPN1MAPK1 | |
| SCHEMBL27842108 | 0.87 | KMT2A (0.49) | KMT2AMEN1ALDH1A1PTPN1MAPK1 | |
| SCHEMBL27842109 | 0.87 | KMT2A (0.49) | KMT2AMEN1ALDH1A1PTPN1MAPK1 | |
| SCHEMBL27469426 | 0.86 | SMN1; SMN2 (0.53) | KMT2AMEN1ALDH1A1PTPN1MAPK1 | |
| SCHEMBL7653623 | 0.86 | SMN1; SMN2 (0.53) | KMT2AMEN1ALDH1A1PTPN1MAPK1 | |
| SCHEMBL383648 | 0.86 | SMN1; SMN2 (0.53) | KMT2AMEN1ALDH1A1PTPN1MAPK1 | |
| SCHEMBL27651792 | 0.85 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1PTPN1MAPK1 | |
| SCHEMBL6016191 | 0.85 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL27953832 | 0.85 | KMT2A (0.48) | KMT2AMEN1ALDH1A1PTPN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250152-A1 | QUINOLINES AS INHIBITORS OF FARNESYL PYROPHOSPHATE SYNTHASE | Novartis AG (CH) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009106586-A1 | QUINOLINES AS INHIBITORS OF FARNESYL PYROPHOSPHATE SYNTHASE | NOVARTIS AG (CH) | 2009-09-03 | — | — | WO | disclosed |
| CN-1352641-A | Isopiperidinecarboxamides for the treatment of integrin-mediated disorders | ORTHO MCNEIL PHARM INC (US) | 2002-06-05 | — | — | CN | disclosed |