Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181579 | 0.92 | ACHE (0.48) | ACHETYMSCYP19A1CYP11B2NOS3 | |
| SCHEMBL31326549 | 0.92 | ACHE (0.48) | ACHETYMSCYP19A1CYP11B2NOS3 | |
| SCHEMBL20368206 | 0.92 | ACHE (0.48) | ACHETYMSCYP19A1CYP11B2NOS3 | |
| SCHEMBL9367273 | 0.92 | ACHE (0.48) | ACHETYMSCYP19A1CYP11B2NOS3 | |
| SCHEMBL9372008 | 0.92 | ACHE (0.48) | ACHETYMSCYP19A1CYP11B2NOS3 | |
| SCHEMBL3470602 | 0.84 | KDM4E (0.51) | ACHETYMSCYP19A1CYP11B2NOTUM | |
| SCHEMBL13383479 | 0.73 | ACHE (0.41) | ACHETYMSNOTUMCSNK2A2CSNK2A1 | |
| SCHEMBL8250749 | 0.73 | ACHE (0.41) | ACHETYMSNOTUMCSNK2A2CSNK2A1 | |
| SCHEMBL14169143 | 0.73 | ACHE (0.41) | ACHETYMSNOTUMCSNK2A2CSNK2A1 | |
| SCHEMBL1339938 | 0.73 | ACHE (0.41) | ACHETYMSNOTUMCSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478616-B1 | INDANES AND INDANONES AND THEIR USE IN PERFUMERY | GIVAUDAN SA (CH) | 2010-09-22 | — | — | EP | disclosed |
| US-7538243-B2 | Indanes and indanones and their use in perfumery | GIVAUDAN SA (CH) | 2009-05-26 | — | — | US | disclosed |
| CN-1329365-C | Indanes and indanones and their use in perfumery | GIVAUDAN SA (CH) | 2007-08-01 | — | — | CN | disclosed |
| US-20050148493-A1 | Indanes and indanones and their use in perfumery | FLACHSMANN FELIX (CH) | 2005-07-07 | — | — | US | disclosed |
| CN-1615294-A | Indanes and indanones and their use in perfumery | GIVAUDAN SA (CH) | 2005-05-11 | — | — | CN | disclosed |
| EP-1340741-A1 | Indane derivatives and their use in perfumery | Givaudan SA (CH) | 2003-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148493-A1 | Indanes and indanones and their use in perfumery | NISCH, CYP1B1, CYP2E1 | ACHE 295/4885TYMS 2114/4885CYP19A1 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.