SCHEMBL3470602

SCHEMBL3470602

CC1CC(=O)c2ccccc21.O=C1CC(c2ccccc2)c2ccccc21

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.51
EEF2K O00418 1/20 0.46
FGFR1 P11362 1/20 0.40
FGFR2 P21802 1/20 0.40
TSHR P16473 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP19A1 P11511 3/20 0.40
CYP11B2 P19099 1/20 0.40
TYMS P04818 1/20 0.40
ACHE P22303 1/20 0.40
ALDH1A1 P00352 2/20 0.39
ALDH2 P05091 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
AR P10275 1/20 0.39
MAOB P27338 1/20 0.39
HSD17B10 Q99714 1/20 0.39
NOTUM Q6P988 1/20 0.37
CSNK2A2 P19784 1/20 0.37
CSNK2A1 P68400 1/20 0.37
CFTR P13569 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8873657 0.89 KDM4E (0.56) KDM4EEEF2KFGFR1FGFR2TSHR
SCHEMBL29657292 0.89 KDM4E (0.56) KDM4EEEF2KFGFR1FGFR2TSHR
SCHEMBL181713 0.89 KDM4E (0.56) KDM4EEEF2KFGFR1FGFR2TSHR
SCHEMBL9367273 0.88 ACHE (0.48) KDM4ETSHRCYP19A1CYP11B2TYMS
SCHEMBL9372008 0.88 ACHE (0.48) KDM4ETSHRCYP19A1CYP11B2TYMS
SCHEMBL181579 0.88 ACHE (0.48) KDM4ETSHRCYP19A1CYP11B2TYMS
SCHEMBL20368206 0.88 ACHE (0.48) KDM4ETSHRCYP19A1CYP11B2TYMS
SCHEMBL31326549 0.88 ACHE (0.48) KDM4ETSHRCYP19A1CYP11B2TYMS
SCHEMBL3404418 0.84 ACHE (0.43) KDM4ETSHRCYP19A1CYP11B2TYMS
SCHEMBL6001645 0.78 RAB9A (0.49) KDM4EEEF2KALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2259358-A2 Photoelectric conversion device and imaging device Fujifilm Corporation (JP) 2010-12-08 EP disclosed