Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | MTOR | P42345 | 1/20 | 0.60 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.60 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.60 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.60 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3765868 | 0.88 | LMNA (0.48) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL3266289 | 0.86 | LMNA (0.64) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL27267985 | 0.85 | LMNA (0.60) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL1981224 | 0.85 | LMNA (0.63) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL29782854 | 0.84 | P2RY6 (0.44) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL5154901 | 0.84 | LMNA (0.62) | LMNATHRBMTORMDM2NCOA1 | |
| Hydrochloric Acid SCHEMBL6946856 | 0.84 | LMNA (0.62) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL635860 | 0.82 | LMNA (0.60) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL3630055 | 0.81 | LMNA (0.59) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL3662232 | 0.81 | LMNA (0.59) | LMNATHRBMTORMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232185-A | Preparation process of monatibavir | 迪维实验室有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-102164939-A | Antiviral nucleoside compounds | METABASIS THERAPEUTICS INC | 2011-08-24 | — | — | CN | disclosed |
| EP-2253621-A1 | A SET OF GELDANAMYCIN DERIVATIVES AND THEIR PREPARATION METHODS | Institute Of Medicinal Biotechnology, Chinese Academy of Medical Sciences (CN) | 2010-11-24 | — | — | EP | disclosed |