Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | MTOR | P42345 | 1/20 | 0.60 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.60 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.60 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.60 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27357267 | 0.99 | LMNA (0.59) | LMNATHRBMTORMDM2NCOA1 | |
| Water SCHEMBL27602266 | 0.99 | LMNA (0.59) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL27267987 | 0.89 | LMNA (0.59) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL3630055 | 0.89 | LMNA (0.59) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL3266289 | 0.86 | LMNA (0.64) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL1981224 | 0.85 | LMNA (0.63) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL5154901 | 0.84 | LMNA (0.62) | LMNATHRBMTORMDM2NCOA1 | |
| Hydrochloric Acid SCHEMBL6946856 | 0.84 | LMNA (0.62) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL3404713 | 0.82 | LMNA (0.60) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL27267985 | 0.82 | LMNA (0.60) | LMNATHRBMTORMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101861320-A | Methods for preparing capecitabine and beta-anomer-rich trialkyl carbonate compound used therein | HANMI PHARM IND CO LTD | 2010-10-13 | — | — | CN | claimed |
| CN-1053194-C | Process for N-acyl-5-fluorocytidine derivatives | HOFFMANN LA ROCHE (CH) | 2000-06-07 | — | — | CN | claimed |
| CN-1126726-A | Process for N-acyl-5-fluorocytidine derivatives | HOFFMANN LA ROCHE (CH) | 1996-07-17 | — | — | CN | claimed |
| CN-102858791-A | Process for producing fluorocytidine derivatives | SCINOPHARM TAIWAN LTD | 2013-01-02 | — | — | CN | disclosed |
| EP-2419135-A1 | COMBINATION THERAPY USING AN ANTI-EGFR AGENT(S) AND IGF-1R SPECIFIC INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010120592-A1 | COMBINATION THERAPY USING AN ANTI-EGFR AGENT(S) AND IGF-1R SPECIFIC INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2010-10-21 | — | — | WO | disclosed |
| CN-101861320-A | Methods for preparing capecitabine and beta-anomer-rich trialkyl carbonate compound used therein | HANMI PHARM IND CO LTD | 2010-10-13 | — | — | CN | disclosed |
| EP-2171447-A1 | HISTONE H2AX (HH2AX) BIOMARKER FOR FTI SENSITIVITY | SCHERING CORPORATION (US) | 2010-04-07 | — | — | EP | disclosed |
| WO-2008156613-A1 | HISTONE H2AX (HH2AX) BIOMARKER FOR FTI SENSITIVITY | SCHERING CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |
| CN-1053194-C | Process for N-acyl-5-fluorocytidine derivatives | HOFFMANN LA ROCHE (CH) | 2000-06-07 | — | — | CN | disclosed |
| CN-1035675-C | Novel process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives | HOFFMANN LA ROCHE (CH) | 1997-08-20 | — | — | CN | disclosed |
| CN-1126726-A | Process for N-acyl-5-fluorocytidine derivatives | HOFFMANN LA ROCHE (CH) | 1996-07-17 | — | — | CN | disclosed |
| CN-1095070-A | Preparation N 4-acyl group-5 '-novel method of deoxidation-5-fluorcytidines | HOFFMANN LA ROCHE (CH) | 1994-11-16 | — | — | CN | disclosed |