Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL140825 | 0.84 | ALDH1A1 (0.41) | POLBKMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL3405495 | 0.84 | NR4A2 (0.56) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL3404051 | 0.83 | EGFR (0.48) | POLBKMT2AMEN1MAPTKDM4E | |
| SCHEMBL3408328 | 0.82 | POLB (0.50) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL144077 | 0.82 | EGFR (0.43) | POLBKMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL30013187 | 0.80 | ALDH1A1 (0.41) | POLBKMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL13010121 | 0.80 | EGFR (0.38) | POLBKMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL3407747 | 0.79 | CNR2 (0.39) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL18468652 | 0.79 | KAT2B (0.41) | POLBKMT2AMAPTALDH1A1LMNA | |
| Iodide SCHEMBL153110 | 0.74 | ALDH1A1 (0.38) | POLBKMT2AMEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |