Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143240 | 0.84 | MAPT (0.50) | POLBCA12CA9CA1CA2 | |
| SCHEMBL3402632 | 0.84 | HTT (0.45) | POLBALDH1A1HSP90AA1PKMCCR6 | |
| SCHEMBL3405019 | 0.82 | POLB (0.42) | POLBCA12CA9ALDH1A1TDP1 | |
| SCHEMBL150147 | 0.80 | MAPK1 (0.49) | POLBCA12CA9CA1CA2 | |
| SCHEMBL3409491 | 0.80 | ALDH1A1 (0.43) | POLBALDH1A1HSP90AA1PKMCCR6 | |
| SCHEMBL3405495 | 0.78 | NR4A2 (0.56) | ALDH1A1HSP90AA1KMT2AGAAMEN1 | |
| SCHEMBL17850892 | 0.76 | ALDH1A1 (0.72) | POLBALDH1A1HSP90AA1PKMCCR6 | |
| SCHEMBL152924 | 0.76 | RORC (0.46) | POLBALDH1A1HSP90AA1PKMCCR6 | |
| SCHEMBL3406738 | 0.76 | KCNMA1 (0.46) | POLBALDH1A1HSP90AA1ATMNPSR1 | |
| SCHEMBL152899 | 0.76 | HSP90AA1 (0.50) | POLBALDH1A1HSP90AA1PKMCCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |