Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1770646 | 0.78 | F2 (0.54) | F2F10 | |
| SCHEMBL3402914 | 0.70 | MAPK1 (0.46) | F2F10 | |
| SCHEMBL1771149 | 0.63 | PPARA (0.43) | — | |
| SCHEMBL1771151 | 0.63 | PPARA (0.43) | — | |
| SCHEMBL24815806 | 0.60 | USP2 (0.51) | — | |
| SCHEMBL10531282 | 0.57 | LEF1 (0.42) | — | |
| SCHEMBL3956299 | 0.56 | MEN1 (0.43) | — | |
| SCHEMBL23976875 | 0.56 | CACNA1I (0.48) | — | |
| SCHEMBL17711779 | 0.55 | KMT2A (0.61) | — | |
| SCHEMBL1294907 | 0.55 | GAA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254881-A1 | CHLOROTHIOPHENE-AMIDES AS INHIBITORS OF COAGULATION FACTORS XA AND THROMBIN | Sanofi-Aventis (FR) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009103440-A1 | CHLOROTHIOPHENE-AMIDES AS INHIBITORS OF COAGULATION FACTORS XA AND THROMBIN | SANOFI-AVENTIS (FR) | 2009-08-27 | — | — | WO | disclosed |