Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 14/20 | 0.40 |
| ▸ | F2 | P00734 | 7/20 | 0.39 |
| ▸ | F9 | P00740 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 2/20 | 0.38 |
| ▸ | PLAT | P00750 | 2/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3409439 | 0.80 | F10 (0.43) | LMNAF10F2TSHR | |
| SCHEMBL1770395 | 0.76 | F10 (0.53) | MAPK1LMNAKMT2AF10F2 | |
| SCHEMBL20560085 | 0.76 | F10 (0.53) | MAPK1LMNAKMT2AF10F2 | |
| SCHEMBL17682014 | 0.72 | MAPK1 (0.59) | MAPK1LMNAKMT2AF10F2 | |
| SCHEMBL3405300 | 0.70 | F2 (0.40) | F10F2 | |
| SCHEMBL1770918 | 0.67 | F10 (0.48) | F10F2F9PLGPLAT | |
| SCHEMBL16201598 | 0.67 | LMNA (0.55) | MAPK1LMNAKMT2AF10F2 | |
| SCHEMBL20615620 | 0.67 | KDM4E (0.64) | MAPK1LMNAKMT2AF10 | |
| Hydrochloric Acid SCHEMBL1770731 | 0.66 | LMNA (0.54) | MAPK1LMNAKMT2AF10F2 | |
| SCHEMBL5625418 | 0.66 | MAPK1 (0.57) | MAPK1LMNAKMT2AF10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254881-A1 | CHLOROTHIOPHENE-AMIDES AS INHIBITORS OF COAGULATION FACTORS XA AND THROMBIN | Sanofi-Aventis (FR) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009103440-A1 | CHLOROTHIOPHENE-AMIDES AS INHIBITORS OF COAGULATION FACTORS XA AND THROMBIN | SANOFI-AVENTIS (FR) | 2009-08-27 | — | — | WO | disclosed |