Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3402632 | 0.82 | HTT (0.45) | SMN1; SMN2HSD17B10POLBTDP1KMT2A | |
| SCHEMBL3404051 | 0.81 | EGFR (0.48) | POLBKMT2AMEN1MAPTKDM4E | |
| SCHEMBL3409107 | 0.78 | GAA (0.44) | HSD17B10POLBKMT2AMAPTALDH1A1 | |
| SCHEMBL3409493 | 0.77 | MAPT (0.48) | SMN1; SMN2POLBAPEX1TDP1KMT2A | |
| SCHEMBL27856168 | 0.76 | KMT2A (0.40) | SMN1; SMN2HSD17B10KMT2AMEN1 | |
| SCHEMBL154776 | 0.76 | KMT2A (0.40) | SMN1; SMN2HSD17B10KMT2AMEN1 | |
| SCHEMBL154774 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2HSD17B10KMT2AMEN1MAPK8 | |
| SCHEMBL3406738 | 0.75 | KCNMA1 (0.46) | SMN1; SMN2HSD17B10POLBKMT2AMEN1 | |
| SCHEMBL14419264 | 0.74 | SMN1; SMN2 (0.71) | SMN1; SMN2HSD17B10POLBKMT2AMEN1 | |
| SCHEMBL11728744 | 0.70 | SMN1; SMN2 (1.00) | SMN1; SMN2HSD17B10POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |