Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3406738 | 0.93 | KCNMA1 (0.46) | HTTALDH1A1NPSR1HSP90AA1ATM | |
| SCHEMBL3404051 | 0.85 | EGFR (0.48) | HTTKCNMA1LMNAMAPTHPGD | |
| SCHEMBL3407763 | 0.84 | ALDH1A1 (0.53) | HTTALDH1A1LMNAMAPTHPGD | |
| SCHEMBL3408328 | 0.84 | POLB (0.50) | ALDH1A1NPSR1HSP90AA1ATMTLR9 | |
| SCHEMBL14058380 | 0.83 | ALDH1A1 (0.45) | HTTALDH1A1NPSR1HSP90AA1ATM | |
| SCHEMBL3409493 | 0.82 | MAPT (0.48) | HTTALDH1A1NPSR1KCNMA1TDP1 | |
| SCHEMBL3405997 | 0.82 | SMN1; SMN2 (0.53) | HTTALDH1A1TDP1LMNAMAPT | |
| SCHEMBL14058541 | 0.82 | ALDH1A1 (0.40) | HTTALDH1A1NPSR1HSP90AA1ATM | |
| SCHEMBL3409107 | 0.81 | GAA (0.44) | ALDH1A1HSP90AA1LMNAMAPTPOLB | |
| SCHEMBL14058532 | 0.76 | ALDH1A1 (0.46) | HTTALDH1A1NPSR1HSP90AA1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |