Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 4/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3518356 | 0.82 | DYRK1A (0.54) | DYRK1ATERTTP53CASP1CASP7 | |
| SCHEMBL30805773 | 0.82 | DYRK1A (0.54) | DYRK1ATERTTP53CASP1CASP7 | |
| SCHEMBL3402945 | 0.81 | TDP1 (0.51) | PLA2G2ATDP1NPC1POLBSMN1; SMN2 | |
| SCHEMBL3400668 | 0.79 | KDM4E (0.47) | DYRK1ATERTTP53CASP1CASP7 | |
| SCHEMBL3123791 | 0.76 | TERT (0.53) | DYRK1ATERTTDP1TP53CASP1 | |
| SCHEMBL30192723 | 0.76 | TERT (0.53) | DYRK1ATERTTDP1TP53CASP1 | |
| SCHEMBL3520974 | 0.76 | DYRK1A (0.42) | DYRK1ATERTTP53SMN1; SMN2KDM4E | |
| SCHEMBL30805770 | 0.74 | DYRK1A (0.56) | DYRK1ATERTTDP1TP53CASP1 | |
| SCHEMBL3290014 | 0.74 | DYRK1A (0.56) | DYRK1ATERTTDP1TP53CASP1 | |
| SCHEMBL29196428 | 0.73 | TERT (0.54) | DYRK1ATERTTP53CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100129800-A1 | POLYMERS AND THEIR USE AS FLUORESCENT LABELS | AYMAMI BOFARULL JUAN | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100129800-A1 | POLYMERS AND THEIR USE AS FLUORESCENT LABELS | CBR3, H1-0, H1-3 | DYRK1A 3219/4885TERT 617/4885PLA2G2A 4529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.