Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725620 | 1.00 | TSHR (0.38) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL2110949 | 0.94 | TSHR (0.33) | TSHRLMNATHRB | |
| SCHEMBL2110946 | 0.94 | TSHR (0.33) | TSHRLMNATHRB | |
| SCHEMBL377049 | 0.85 | TSHR (0.32) | TSHRLMNATHRB | |
| SCHEMBL440143 | 0.85 | TSHR (0.32) | TSHRLMNATHRB | |
| SCHEMBL976968 | 0.85 | TSHR (0.32) | TSHRLMNATHRB | |
| SCHEMBL3778589 | 0.83 | LMNA (0.30) | TSHRLMNA | |
| SCHEMBL5078419 | 0.83 | ALDH1A1 (0.30) | TSHRLMNAALDH1A1 | |
| SCHEMBL11054804 | 0.83 | LMNA (0.30) | TSHRLMNA | |
| SCHEMBL6283644 | 0.83 | TSHR (0.32) | TSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117645711-A | Pyrrolo-pyrrole-dione bipolar ion-electron mixed organic semiconductor and preparation method and application thereof | 中山大学 | 2024-03-05 | — | — | CN | claimed |
| US-10566539-B2 | Organic semiconductor compounds and methods of use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-02-18 | — | — | US | claimed |
| US-20170186961-A1 | ORGANIC SEMICONDUCTOR COMPOUNDS AND METHODS OF USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-06-29 | — | — | US | claimed |
| WO-2015171640-A1 | ORGANIC SEMICONDUCTOR COMPOUNDS AND METHODS OF USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-11-12 | — | — | WO | claimed |
| WO-2002020694-A1 | LOW MOLECULAR CHROMOPHORE COMPOUNDS AND ELECTROLUMINESCENCE DISPLAY DEVICE COMPRISING THE SAME | VISTORM CO., LTD. (KR) | 2002-03-14 | — | — | WO | claimed |
| CN-120136857-A | Acceptor unit with skeleton containing thiophene modified benzoxadiazole derivative, side chain alkyl substitution and main chain vinyl bridging, and preparation and application thereof | 复旦大学 | 2025-06-13 | — | — | CN | disclosed |
| EP-4539840-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | Neuron23, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| CN-119730846-A | Kinase modulators and methods of use thereof | 神经元23公司 | 2025-03-28 | — | — | CN | disclosed |
| US-12152182-B2 | Polymer nanoparticles for afterglow molecular imaging | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2024-11-26 | — | — | US | disclosed |
| WO-2023244788-A9 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2024-09-12 | — | — | WO | disclosed |
| CN-117645711-A | Pyrrolo-pyrrole-dione bipolar ion-electron mixed organic semiconductor and preparation method and application thereof | 中山大学 | 2024-03-05 | — | — | CN | disclosed |
| CN-117624559-A | Dithiophene aza isoindigo polymer and preparation method and application thereof | 中国科学院化学研究所 | 2024-03-01 | — | — | CN | disclosed |
| US-4970229-A | ANTIINFLAMMATORY AGENTS | G. D. SEARLE & CO. (US) | 1990-11-13 | — | — | US | disclosed |
| US-4970234-A | ANTIINFLAMMATORY AGENTS | G. D. SEARLE & CO. (US) | 1990-11-13 | — | — | US | disclosed |
| WO-1990011272-A1 | NEW LEUCOTRIENE B4 DERIVATIVES, A METHOD OF PREPARING THEM, AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1990-10-04 | — | — | WO | disclosed |
| US-4855324-A | ANTIINFLAMMATORY AGENTS | G. D. SEARLE & CO. (US) | 1989-08-08 | — | — | US | disclosed |
| EP-0319900-A2 | Furyl, phenylene and thienyl leukotriene B4 analogues | G.D. Searle & Co. (US) | 1989-06-14 | — | — | EP | disclosed |
| US-4477388-A | CHEMICAL INTERMEDIATES FOR PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1984-10-16 | — | — | US | disclosed |
| US-4233231-A | USED FOR PREPARATION OF CHEMICAL INTERMEDIATES OF PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1980-11-11 | — | — | US | disclosed |
| US-4038308-A | BRONCHODILATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12152182-B2 | Polymer nanoparticles for afterglow molecular imaging | CD68, ALG1, MB | TSHR 3164/4885LMNA 182/4885THRB 2637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.