SCHEMBL340717

SCHEMBL340717

CCCC[Si](CCCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
LMNA P02545 1/20 0.33
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23365053 0.92 TSHR (0.37) TSHRLMNATHRB
SCHEMBL23365049 0.89 TSHR (0.42) TSHRLMNATHRB
SCHEMBL23365042 0.89 TSHR (0.42) TSHRLMNATHRB
SCHEMBL23365037 0.89 TSHR (0.42) TSHRLMNATHRB
SCHEMBL23365103 0.80 ADRB2 (0.39) TSHRLMNATHRB
SCHEMBL23365097 0.80 ADRB2 (0.33) TSHRLMNATHRB
SCHEMBL340450 0.77 TSHR (0.33) TSHRLMNATHRB
SCHEMBL23365033 0.72 TSHR (0.35) TSHRLMNATHRB
SCHEMBL23365108 0.72 ADRB2 (0.38) TSHRLMNATHRB
SCHEMBL23365051 0.70 THRB (0.40) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220403056-A1 CURED RUBBER NETWORK WITH COVALENT AND HYDROGEN-BONDED CROSSLINKS BRIDGESTONE CORPORATION (JP) 2022-12-22 US disclosed
EP-4058487-A2 CURED RUBBER NETWORK WITH COVALENT AND HYDROGEN-BONDED CROSSLINKS BRIDGESTONE CORPORATION (JP) 2022-09-21 EP disclosed
WO-2021097455-A2 CURED RUBBER NETWORK WITH COVALENT AND HYDROGEN-BONDED CROSSLINKS BRIDGESTONE CORPORATION (JP) 2021-05-20 WO disclosed
EP-2065455-B1 Pressure-sensitive adhesive tape NITTO DENKO CORP (JP) 2012-05-16 EP disclosed
US-20120015100-A1 Pressure-Sensitive Adhesive Tape NITTO DENKO CORPORATION (JP) 2012-01-19 US disclosed
US-8067508-B2 Compositions consisting of partially silyl-terminated polymers HENKEL AG & CO. KGAA (DE) 2011-11-29 US disclosed
EP-2383321-A2 Process for producing an adhesive composition and adhesive tape comprising an adhesive composition produced by said process Nitto Denko Corporation (JP) 2011-11-02 EP disclosed
US-20100081757-A1 COMPOSITIONS CONSISTING OF PARTIALLY SILYL-TERMINATED POLYMERS HENKEL AG & CO. KGAA (DE) 2010-04-01 US disclosed
US-20090142593-A1 PRESSURE-SENSITIVE ADHESIVE TAPE NITTO DENKO CORPORATION (JP) 2009-06-04 US disclosed
EP-2065455-A1 Pressure-sensitive adhesive tape NITTO DENKO CORPORATION (JP) 2009-06-03 EP disclosed