Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3408234 | 0.80 | KDM4E (0.54) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL1061379 | 0.76 | KDM4E (0.64) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL7242790 | 0.75 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL3411281 | 0.74 | EGFR (0.52) | ALDH1A1MEN1KMT2ANPC1ADORA3 | |
| SCHEMBL1058188 | 0.74 | KDM5A (0.68) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL14829865 | 0.74 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL31298134 | 0.74 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL2637577 | 0.74 | MAPT (0.53) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL2885446 | 0.73 | NR4A2 (0.71) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL11307581 | 0.73 | KDM4E (0.72) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2264035-A1 | Glycine B antagonists | Merz Pharma GmbH & Co. KGaA (DE) | 2010-12-22 | — | — | EP | disclosed |