Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL525028 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL22686437 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL42945 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL29587574 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL1291555 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL23012792 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL20668547 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL17240265 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL21555662 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL1439656 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6765 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260146195-A1 | SINTERING POWDER | ALPHA ASSEMBLY SOLUTIONS INC. (US) | 2026-05-28 | — | — | US | claimed |
| CN-120311480-B | Polyamide 6 high-conductivity fabric for textile-based electronic products and preparation method thereof | QINGDAO UNIVERSITY (CN) | 2026-05-26 | — | — | CN | claimed |
| EP-4743053-A1 | ANTIMICROBIAL SYNERGIES | Symrise AG (DE) | 2026-05-20 | — | — | EP | claimed |
| WO-2026099171-A1 | ANTI-MICROBIAL COMPOSITION AND PREPARATION PROCESS AND USE THEREOF | CLARIANT INTERNATIONAL LTD (CH) | 2026-05-15 | — | — | WO | claimed |
| CN-122004238-A | Antimicrobial compositions, methods of making and uses thereof | 科莱恩国际有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122007402-A | Silver paste and silver sintered body | 丰田自动车株式会社 | 2026-05-12 | — | — | CN | claimed |
| CN-122011838-A | Composite particle-free conductive ink and preparation method and application thereof | 丰宾电子科技股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-12605477-B2 | Compositions and methods for decontamination of surfaces | Aviraban, LLC (US) | 2026-04-21 | — | — | US | claimed |
| US-20260092186-A1 | METAL NANOPARTICLE INK | UNIV IOWA STATE RES FOUND INC (US) | 2026-04-02 | — | — | US | claimed |
| EP-4554551-B1 | 3-HYDROXYPROPYLESTERS AS ANTIMICROBIAL AGENTS | SYMRISE AG (DE) | 2026-03-11 | — | — | EP | claimed |
| US-4299682-A | HAVING A POROUS LAYER MADE BY DECOMPOSING A GROUP EIGHT SALT OF A CARBOXYLIC ACID | ASAHI GLASS COMPANY, LTD. (JP) | 1981-11-10 | — | — | US | claimed |
| US-4229321-A | Process for making a silver catalyst | TEXACO DEVELOPMENT CORP. (US) | 1980-10-21 | — | — | US | claimed |
| US-4224194-A | CESIUM OR RUBIDIUM PROMOTED SILVER EPOXIDATION CATALYST | TEXACO DEVELOPMENT CORP. (US) | 1980-09-23 | — | — | US | claimed |
| EP-0014896-A1 | Gas diffusion electrode | ASAHI GLASS COMPANY LTD. (JP) | 1980-09-03 | — | — | EP | claimed |
| US-4206128-A | EPOXIDIZING ETHYLENE, SILVER CATALYST | TEXACO DEVELOPMENT CORPORATION (US) | 1980-06-03 | — | — | US | claimed |
| US-4121938-A | Photographic material containing TiO2, soluble Cu(II) salt, and soluble silver salt and the use thereof in physical development | FUJI PHOTO FILM CO., LTD. (JP) | 1978-10-24 | — | — | US | claimed |
| US-4097414-A | METALLIC SILVER, CESIUM PROMOTER, INORGANIC SUPPORT | TEXACO DEVELOPMENT CORP. (US) | 1978-06-27 | — | — | US | claimed |
| US-3990833-A | Switching devices for photoflash unit | GENERAL ELECTRIC COMPANY (US) | 1976-11-09 | — | — | US | claimed |
| US-3981916-A | Reduction of nitroparaffin substrates to their corresponding oximes using a silver salt catalyst | TEXACO INC. (US) | 1976-09-21 | — | — | US | claimed |
| US-3964255-A | Method of inflating an automobile passenger restraint bag | SPECIALTY PRODUCTS DEVELOPMENT CORPORATION (US) | 1976-06-22 | — | — | US | claimed |