Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL1291555 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL42945 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL22686437 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL29587574 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL23012792 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL21555662 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL276988 | 0.94 | CA4 (1.00) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL20668544 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL9171055 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL37799 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119899875-A | High throughput reductive dehalogenation process based on microorganisms | 北京师范大学珠海校区 | 2025-04-29 | — | — | CN | claimed |
| CN-119776293-A | ArsL mutant and application thereof in synthesis of Arsinothricin | 上海交通大学 | 2025-04-08 | — | — | CN | claimed |
| US-20230265749-A1 | METHODOLOGY TO IMPROVE THE EFFICIENCY OF GRAVITY DRAINAGE CO2 GAS INJECTION PROCESSES | SAUDI ARABIAN OIL COMPANY (SA) | 2023-08-24 | — | — | US | claimed |
| CN-115925011-A | Method for degrading 1, 2-dichloroethane by using titanium (III) citrate in cooperation with vitamin B12 and application of method | 浙江工业大学 | 2023-04-07 | — | — | CN | claimed |
| US-20120295818-A1 | METHOD OF MULTI PATHOGEN DETECTION | HITACHI CHEMICAL RESEARCH CENTER, INC. (US) | 2012-11-22 | — | — | US | claimed |
| WO-2011090803-A1 | METHOD OF MULTI PATHOGEN DETECTION | HITACHI CHEMICAL CO., LTD. (JP) | 2011-07-28 | — | — | WO | claimed |
| US-20090159539-A1 | Catalytically Treating Water Contaminated With Halogenated Organic Compounds | YEDA RESEARCH AND DEVELOPMENT CO., LTD. WEIZMANN INSTITUTE OF SCIENCE (IL) | 2009-06-25 | — | — | US | claimed |
| EP-1945318-A2 | CATALYTICALLY TREATING WATER CONTAMINATED WITH HALOGENATED ORGANIC COMPOUNDS | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2008-07-23 | — | — | EP | claimed |
| WO-2007054936-A2 | CATALYTICALLY TREATING WATER CONTAMINATED WITH HALOGENATED ORGANIC COMPOUNDS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2007-05-18 | — | — | WO | claimed |
| EP-0552279-A4 | ASSAY FOR MOTILE FACULTATIVE ANAEROBIC PATHOGENS | UNIV KANSAS STATE (US) | 1994-06-01 | — | — | EP | claimed |
| EP-0552279-A1 | ASSAY FOR MOTILE FACULTATIVE ANAEROBIC PATHOGENS | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1993-07-28 | — | — | EP | claimed |
| WO-1992006214-A1 | ASSAY FOR MOTILE FACULTATIVE ANAEROBIC PATHOGENS | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1992-04-16 | — | — | WO | claimed |
| EP-4739145-A1 | METHOD FOR ESTABLISHING A COMBINATION THERAPY AND CORRESPONDING PHARMACEUTICAL AND NUTRITIONAL COMBINATIONS | PharmaBiome AG (CH) | 2026-05-13 | — | — | EP | disclosed |
| CN-120060228-A | Polypeptides for biosynthesis of 1, 2-propanediol and uses thereof | 天津大学 | 2025-05-30 | — | — | CN | disclosed |
| CN-120060384-A | Biological method for preparing 1, 2-propanediol | 天津大学 | 2025-05-30 | — | — | CN | disclosed |
| CN-119899875-A | High throughput reductive dehalogenation process based on microorganisms | 北京师范大学珠海校区 | 2025-04-29 | — | — | CN | disclosed |
| US-5200343-A | Pretreating the bacteria by inducing cell in presence of 1,3-substituted phenyl without being metabolized and pyruvic acid, ester, acid salt as electron donor | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 1993-04-06 | — | — | US | disclosed |
| US-5187070-A | Incubation in culture containing growth promoting oxygen-reactive enzyme and esculin indicator | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1993-02-16 | — | — | US | disclosed |
| WO-1992009689-A1 | PURIFIED THERMOSTABLE $i(PYROCOCCUS FURIOSUS) | STRATAGENE (US) | 1992-06-11 | — | — | WO | disclosed |
| EP-0385415-A1 | Process for producing NADH oxidase | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1990-09-05 | — | — | EP | disclosed |