Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 18/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 16/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3411685 | 0.78 | SIGMAR1 (0.64) | OPRL1OPRM1OPRK1 | |
| SCHEMBL3413521 | 0.75 | OPRL1 (1.00) | OPRL1OPRM1OPRK1 | |
| SCHEMBL3407434 | 0.74 | OPRL1 (0.68) | OPRL1OPRM1OPRK1 | |
| SCHEMBL12520508 | 0.74 | OPRL1 (0.68) | OPRL1OPRM1OPRK1 | |
| SCHEMBL19093376 | 0.73 | OPRL1 (0.66) | OPRL1OPRM1OPRK1 | |
| SCHEMBL1349548 | 0.73 | ALDH1A1 (0.37) | — | |
| SCHEMBL22101935 | 0.71 | OPRL1 (0.82) | OPRL1OPRM1OPRK1 | |
| SCHEMBL3413008 | 0.71 | OPRL1 (0.61) | OPRL1OPRM1OPRK1 | |
| SCHEMBL9726985 | 0.71 | ALDH1A1 (0.36) | — | |
| SCHEMBL15194472 | 0.71 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2502907-B1 | Substituted 4-aminocyclohexane derivatives | GRUENENTHAL GMBH (DE) | 2018-08-29 | — | — | EP | disclosed |
| EP-2518052-B1 | Substituted 4-aminocyclohexane derivatives | GRUENENTHAL GMBH (DE) | 2017-12-20 | — | — | EP | disclosed |
| EP-2260021-B1 | SUBSTITUTED 4-AMINOCYCLOHEXANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2014-04-23 | — | — | EP | disclosed |
| EP-2518052-A1 | Substituted 4-aminocyclohexane derivatives | Grünenthal GmbH (DE) | 2012-10-31 | — | — | EP | disclosed |
| EP-2502907-A1 | Substituted 4-aminocyclohexane derivatives | Grünenthal GmbH (DE) | 2012-09-26 | — | — | EP | disclosed |
| EP-2260021-A1 | SUBSTITUTED 4-AMINOCYCLOHEXANE DERIVATIVES | Grünenthal GmbH (DE) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009118168-A1 | SUBSTITUTED 4-AMINOCYCLOHEXANE DERIVATIVES | Grünenthal GmbH (DE) | 2009-10-01 | — | — | WO | disclosed |